5KRV
1-deoxy-D-xylulose 5-phosphate reductoisomerase from Vibrio vulnificus in complex Arginine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0030604 | molecular_function | 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051484 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process |
| A | 0070402 | molecular_function | NADPH binding |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019288 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0030604 | molecular_function | 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051484 | biological_process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process |
| B | 0070402 | molecular_function | NADPH binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | TYR286 |
| A | PRO287 |
| A | ARG289 |
| B | PRO161 |
| B | TYR262 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | HIS153 |
| A | GLU234 |
| A | LEU122 |
| A | PRO148 |
| A | VAL149 |
| A | ASP150 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | PRO25 |
| A | PHE28 |
| A | SER29 |
| A | VAL30 |
| A | TRP49 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | GLN47 |
| A | ARG48 |
| A | THR300 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | PRO203 |
| A | PRO203 |
| A | GLU204 |
| A | GLU204 |
| A | LEU347 |
| A | LEU347 |
| A | ARG349 |
| A | ARG349 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue ARG A 507 |
| Chain | Residue |
| A | ALA57 |
| A | ASN58 |
| A | LYS59 |
| A | GLN82 |
| A | ARG387 |
| A | HOH669 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 508 |
| Chain | Residue |
| A | SER186 |
| A | ASN227 |
| A | LYS228 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SRT B 501 |
| Chain | Residue |
| B | LYS59 |
| B | GLY81 |
| B | GLN82 |
| B | GLU83 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | LEU122 |
| B | ASN124 |
| B | LYS125 |
| B | PRO148 |
| B | VAL149 |
| B | ASP150 |
| B | HIS153 |
| B | GLU234 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | GLU197 |
| B | GLN205 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | PHE312 |
| B | ALA319 |
| B | HOH602 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | THR10 |
| B | ASP36 |
| B | SER37 |
| B | ASN38 |
| B | HOH604 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 34 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00183","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
