5KRL
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the A-CD ring estrogen, (1S,7aS)-5-(2-chloro-4-hydroxyphenyl)-7a-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-1-ol
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | binding site for residue 6WR A 601 |
Chain | Residue |
A | MET343 |
A | LEU346 |
A | GLU353 |
A | LEU387 |
A | MET388 |
A | GLY521 |
A | HIS524 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue 6WR B 601 |
Chain | Residue |
B | MET388 |
B | HIS524 |
B | LEU346 |
B | GLU353 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
C | SER699 | |
D | SER699 | |
Chain | Residue | Details |
A | ILE358-LEU378 | |
A | ARG394-VAL418 | |
B | ILE358-LEU378 | |
B | ARG394-VAL418 | |
Chain | Residue | Details |
A | ALA340 | |
B | ALA340 | |
Chain | Residue | Details |
A | SER433 | |
B | SER433 | |