5KRD
Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN and 2-iodophenol (2IP)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0140616 | molecular_function | iodotyrosine deiodinase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0140616 | molecular_function | iodotyrosine deiodinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue FMN A 301 |
| Chain | Residue |
| A | ARG34 |
| A | GLU149 |
| A | SER150 |
| A | THR171 |
| A | HIS172 |
| A | THR173 |
| A | ARG212 |
| A | 6X8302 |
| A | HOH413 |
| A | HOH416 |
| A | HOH419 |
| A | ARG35 |
| A | HOH434 |
| A | HOH456 |
| A | THR36 |
| A | ARG38 |
| A | PRO61 |
| A | SER62 |
| A | GLY63 |
| A | HIS65 |
| A | TYR146 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue 6X8 A 302 |
| Chain | Residue |
| A | ALA64 |
| A | FMN301 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue FMN B 301 |
| Chain | Residue |
| B | ARG34 |
| B | ARG35 |
| B | THR36 |
| B | ARG38 |
| B | PRO61 |
| B | SER62 |
| B | TYR146 |
| B | GLU149 |
| B | SER150 |
| B | THR171 |
| B | THR173 |
| B | ARG212 |
| B | 6X8302 |
| B | HOH411 |
| B | HOH422 |
| B | HOH428 |
| B | HOH430 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue 6X8 B 302 |
| Chain | Residue |
| B | ALA64 |
| B | FMN301 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28157283, ECO:0007744|PDB:5KO7, ECO:0007744|PDB:5KO8, ECO:0007744|PDB:5KRD |
| Chain | Residue | Details |
| A | ARG34 | |
| A | THR171 | |
| A | ARG212 | |
| B | ARG34 | |
| B | THR171 | |
| B | ARG212 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28157283, ECO:0007744|PDB:5KO8, ECO:0007744|PDB:5KRD |
| Chain | Residue | Details |
| A | PRO61 | |
| B | PRO61 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28157283, ECO:0007744|PDB:5KO8 |
| Chain | Residue | Details |
| A | GLU91 | |
| A | TYR95 | |
| A | LYS116 | |
| B | GLU91 | |
| B | TYR95 | |
| B | LYS116 |
