5KQJ

Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals Substrate-Regulated Conformation Dynamics

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008871	molecular_function	aminoglycoside 2''-nucleotidyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	91
Details	Region: {"description":"N-terminal domain","evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28734024","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	84
Details	Region: {"description":"C-terminal domain","evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28734024","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WQL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25564464","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WQL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---