5KPZ

PANK3-ADP-PhosphoPantothenate complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004594	molecular_function	pantothenate kinase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0015937	biological_process	coenzyme A biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0019842	molecular_function	vitamin binding
A	0042803	molecular_function	protein homodimerization activity
A	1905502	molecular_function	acetyl-CoA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue PAZ A 401

Chain	Residue
A	GLY20
A	ALA269
A	ADP402
A	MG403
A	HOH504
A	HOH508
A	HOH518
A	HOH519
A	HOH531
A	GLU138
A	SER192
A	GLY193
A	VAL194
A	SER195
A	ARG207
A	THR211
A	VAL268

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site_id	AC2
Number of Residues	17
Details	binding site for residue ADP A 402

Chain	Residue
A	GLY19
A	GLY20
A	THR21
A	LEU22
A	LYS24
A	GLY191
A	SER192
A	GLY215
A	GLY216
A	PHE231
A	ASN322
A	PHE323
A	ARG325
A	PAZ401
A	MG403
A	HOH502
A	HOH519

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site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 403

Chain	Residue
A	PAZ401
A	ADP402
A	HOH501
A	HOH508
A	HOH515
A	HOH519

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000269|PubMed:27555321

Chain	Residue	Details
A	GLU138

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:17631502

Chain	Residue	Details
A	SER192

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:17631502, ECO:0000269|PubMed:20797618

Chain	Residue	Details
A	SER195
A	ARG207

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