5KP7
Crystal Structure of the Curacin Biosynthetic Pathway HMG Synthase in Complex with Holo Donor-ACP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004421 | molecular_function | hydroxymethylglutaryl-CoA synthase activity |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0010142 | biological_process | farnesyl diphosphate biosynthetic process, mevalonate pathway |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | SER353 |
| A | LYS410 |
| A | LYS415 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | TYR231 |
| A | VAL235 |
| A | ARG320 |
| A | HOH840 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue PNS B 100 |
| Chain | Residue |
| A | MET39 |
| A | PHE163 |
| A | PRO166 |
| A | SER167 |
| A | SER216 |
| A | MET256 |
| B | SER39 |
| B | ARG42 |
| B | HOH206 |
| B | HOH208 |
| A | ARG33 |
| A | LEU37 |
