5KOW
Structure of rifampicin monooxygenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | binding site for residue FAD A 501 |
| Chain | Residue |
| A | GLY8 |
| A | GLN98 |
| A | CYS120 |
| A | GLU121 |
| A | VAL122 |
| A | CYS150 |
| A | ASP151 |
| A | GLY152 |
| A | THR156 |
| A | LEU176 |
| A | GLY275 |
| A | GLY10 |
| A | ASP276 |
| A | PRO283 |
| A | GLN287 |
| A | GLY288 |
| A | LEU289 |
| A | ASN290 |
| A | HOH608 |
| A | HOH612 |
| A | HOH619 |
| A | HOH641 |
| A | PRO11 |
| A | THR12 |
| A | LEU30 |
| A | GLU31 |
| A | LYS32 |
| A | ARG41 |
| A | SER42 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 502 |
| Chain | Residue |
| A | GLY162 |
| A | GLY407 |
| A | ARG409 |
| A | HOH666 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27557658, ECO:0000269|PubMed:29578336, ECO:0007744|PDB:5KOW, ECO:0007744|PDB:5KOX, ECO:0007744|PDB:6C7S |
| Chain | Residue | Details |
| A | THR12 | |
| A | ASN290 | |
| A | GLU31 | |
| A | LYS32 | |
| A | ARG41 | |
| A | GLN98 | |
| A | VAL122 | |
| A | THR156 | |
| A | ASP276 | |
| A | LEU289 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27557658, ECO:0000269|PubMed:29578336, ECO:0007744|PDB:5KOX, ECO:0007744|PDB:6C7S |
| Chain | Residue | Details |
| A | ARG43 | |
| A | GLY285 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29578336, ECO:0007744|PDB:6C7S |
| Chain | Residue | Details |
| A | ARG196 |
