5KLL
Crystal structure of 2-hydroxymuconate-6-semialdehyde derived tautomeric intermediate in 2-aminomuconate 6-semialdehyde dehydrogenase N169D
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 6UN A 601 |
| Chain | Residue |
| A | ARG120 |
| A | PHE470 |
| A | ASP169 |
| A | LEU174 |
| A | TRP177 |
| A | GLU268 |
| A | VAL301 |
| A | CYS302 |
| A | TYR462 |
| A | ARG464 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 602 |
| Chain | Residue |
| A | ASN37 |
| A | ILE38 |
| A | ASP105 |
| A | GLU196 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue 6UN B 601 |
| Chain | Residue |
| B | ARG120 |
| B | ASP169 |
| B | LEU170 |
| B | LEU174 |
| B | TRP177 |
| B | GLU268 |
| B | VAL301 |
| B | CYS302 |
| B | TYR462 |
| B | ARG464 |
| B | PHE470 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 602 |
| Chain | Residue |
| B | ASN37 |
| B | ILE38 |
| B | ASP105 |
| B | GLU196 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue 6UN C 601 |
| Chain | Residue |
| C | ARG120 |
| C | ASP169 |
| C | LEU174 |
| C | TRP177 |
| C | GLU268 |
| C | VAL301 |
| C | CYS302 |
| C | TYR462 |
| C | ARG464 |
| C | PHE470 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 602 |
| Chain | Residue |
| C | ASN37 |
| C | ILE38 |
| C | ASP105 |
| C | GLU196 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue 6UN D 601 |
| Chain | Residue |
| D | ARG120 |
| D | ASP169 |
| D | LEU174 |
| D | TRP177 |
| D | GLU268 |
| D | VAL301 |
| D | CYS302 |
| D | TYR462 |
| D | ARG464 |
| D | PHE470 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue NA D 602 |
| Chain | Residue |
| D | ASN37 |
| D | ILE38 |
| D | ASP105 |
| D | GLU196 |
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. FtNSGQVCLCSE |
| Chain | Residue | Details |
| A | PHE295-GLU306 |
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. FELGGKNA |
| Chain | Residue | Details |
| A | PHE267-ALA274 |
