5KHK

HCN2 CNBD in complex with 2-aminopurine riboside-3', 5'-cyclic monophosphate (2-NH2-cPuMP)

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue 6SZ A 701

Chain	Residue
A	VAL564
A	THR592
A	ALA593
A	ARG632
A	ILE636
A	MET572
A	LEU574
A	PHE580
A	GLY581
A	GLU582
A	ILE583
A	CYS584
A	ARG591

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Functional Information from PROSITE/UniProt

site_id	PS00888
Number of Residues	17
Details	CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrEGTiGKkMYFIqhG

Chain	Residue	Details
A	ILE544-GLY560

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:18367452, ECO:0000269|PubMed:19525958

Chain	Residue	Details
A	GLY581
A	ARG591
A	ARG632

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKG/PRKG2 => ECO:0000269|PubMed:21347269

Chain	Residue	Details
A	SER641

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