5KGW

HIV1 catalytic core domain in complex with inhibitor: (2~{S})-2-[3-(3,4-dihydro-2~{H}-chromen-6-yl)-1-methyl-indol-2-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 301

Chain	Residue
A	LYS71
A	ARG166
A	HIS171
A	LEU172
A	HOH409

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site_id	AC2
Number of Residues	2
Details	binding site for residue SO4 A 302

Chain	Residue
A	THR66
A	HIS67

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site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 A 303

Chain	Residue
A	SER123
A	THR125
A	LYS186
A	HOH422
A	THR93
A	GLY94

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site_id	AC4
Number of Residues	10
Details	binding site for residue 7SK A 304

Chain	Residue
A	GLN95
A	LEU102
A	THR125
A	ALA129
A	TRP132
A	ALA169
A	GLU170
A	HIS171
A	THR174
A	MET178

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
A	ASP64
A	ASP116

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P04585

Chain	Residue	Details
A	GLU152

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