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5KG6

Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Ca2+ for 60s

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue MN A 501
ChainResidue
AASP13
AASP115
AGLU116
AMN502
ADTP506
AHOH785
PDT8
PDA9

site_idAC2
Number of Residues7
Detailsbinding site for residue MN A 502
ChainResidue
AMET14
AASP115
AMN501
ADTP506
ADPO507
PDA9
AASP13

site_idAC3
Number of Residues8
Detailsbinding site for residue GOL A 503
ChainResidue
AARG24
APRO244
ASER248
AGLY276
AHOH620
AHOH622
AHOH666
AHOH738

site_idAC4
Number of Residues7
Detailsbinding site for residue GOL A 504
ChainResidue
AGLU94
AALA95
AGLU98
AARG303
AHOH692
AHOH722
AHOH756

site_idAC5
Number of Residues10
Detailsbinding site for residue GOL A 505
ChainResidue
AASN26
AHIS28
AGLY271
AILE272
AGLU273
ATYR274
AGLU277
AHOH601
AHOH604
AHOH727

site_idAC6
Number of Residues32
Detailsbinding site for residue DTP A 506
ChainResidue
AASP13
AMET14
AASP15
ACYS16
APHE17
APHE18
AILE48
AALA49
ATYR52
AARG55
AARG61
AASP115
ALYS231
AMN501
AMN502
ADPO507
AHOH625
AHOH631
AHOH656
AHOH688
AHOH785
AHOH806
PDT8
PDA9
PMN101
PHOH205
PHOH213
PHOH217
PHOH218
TDT3
TDT4
TDA5

site_idAC7
Number of Residues18
Detailsbinding site for residue DPO A 507
ChainResidue
AASP13
AMET14
AASP15
ACYS16
APHE17
ATYR52
AARG55
AARG61
AASP115
ALYS231
AMN502
ADTP506
AHOH625
AHOH631
AHOH656
AHOH806
PDA9
PMN101

site_idAC8
Number of Residues8
Detailsbinding site for residue MN P 101
ChainResidue
AARG61
ADTP506
ADPO507
AHOH631
AHOH688
AHOH806
PDA9
PHOH218

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO
ChainResidueDetails
AASP13
AMET14
AASP115
AGLU116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197
ChainResidueDetails
AARG61

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PDB entries from 2024-11-06

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