5KG5

Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Cd2+ for 60s

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue MN A 501

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	MN502
A	DTP506
A	HOH799
P	DT8
P	DA9

---

site_id	AC2
Number of Residues	7
Details	binding site for residue MN A 502

Chain	Residue
A	MET14
A	ASP115
A	MN501
A	DTP506
A	DPO507
P	DA9
A	ASP13

---

site_id	AC3
Number of Residues	9
Details	binding site for residue GOL A 503

Chain	Residue
A	ARG24
A	PRO244
A	PHE247
A	SER248
A	GLY276
A	HOH649
A	HOH662
A	HOH684
A	HOH709

---

site_id	AC4
Number of Residues	7
Details	binding site for residue GOL A 504

Chain	Residue
A	GLU94
A	ALA95
A	GLU98
A	ARG303
A	HOH633
A	HOH655
A	HOH809

---

site_id	AC5
Number of Residues	10
Details	binding site for residue GOL A 505

Chain	Residue
A	ASN26
A	HIS28
A	GLY271
A	ILE272
A	GLU273
A	TYR274
A	GLU277
A	HOH607
A	HOH609
A	HOH755

---

site_id	AC6
Number of Residues	33
Details	binding site for residue DTP A 506

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ILE114
A	ASP115
A	LYS231
A	MN501
A	MN502
A	DPO507
A	HOH632
A	HOH643
A	HOH667
A	HOH712
A	HOH764
A	HOH799
A	HOH815
P	DT8
P	DA9
P	MN101
P	HOH204
P	HOH208
P	HOH215
T	DT3
T	DT4
T	DA5

---

site_id	AC7
Number of Residues	18
Details	binding site for residue DPO A 507

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MN502
A	DTP506
A	HOH632
A	HOH643
A	HOH667
A	HOH764
P	DA9
P	MN101

---

site_id	AC8
Number of Residues	8
Details	binding site for residue MN P 101

Chain	Residue
P	HOH215
A	ARG61
A	DTP506
A	DPO507
A	HOH667
A	HOH712
A	HOH764
P	DA9

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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