5KFW

Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue MG A 501

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	CA502
A	MG503
A	DTP507
P	DT8
P	DA9
P	HOH212

---

site_id	AC2
Number of Residues	8
Details	binding site for residue CA A 502

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
A	DTP507
A	DPO508
A	K509
P	DA9

---

site_id	AC3
Number of Residues	8
Details	binding site for residue MG A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
A	DTP507
A	DPO508
A	K509
P	DA9

---

site_id	AC4
Number of Residues	8
Details	binding site for residue GOL A 504

Chain	Residue
A	ARG24
A	PRO244
A	SER248
A	GLY276
A	HOH621
A	HOH654
A	HOH697
A	HOH722

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 505

Chain	Residue
A	GLU94
A	ALA95
A	GLU98
A	ARG303
A	HOH679
A	HOH713
A	HOH730

---

site_id	AC6
Number of Residues	10
Details	binding site for residue GOL A 506

Chain	Residue
A	ASN26
A	PRO27
A	HIS28
A	GLY271
A	GLU273
A	TYR274
A	GLU277
A	HOH608
A	HOH649
A	HOH694

---

site_id	AC7
Number of Residues	35
Details	binding site for residue DTP A 507

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ILE114
A	ASP115
A	LYS231
A	MG501
A	CA502
A	MG503
A	DPO508
A	K509
A	HOH605
A	HOH631
A	HOH645
A	HOH653
A	HOH668
A	HOH704
P	DT8
P	DA9
P	MG101
P	HOH201
P	HOH212
P	HOH214
P	HOH215
P	HOH225
T	DT3
T	DT4
T	DA5

---

site_id	AC8
Number of Residues	18
Details	binding site for residue DPO A 508

Chain	Residue
A	HOH668
A	HOH704
P	DA9
P	MG101
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	TYR52
A	ARG55
A	ASP115
A	LYS231
A	CA502
A	MG503
A	DTP507
A	HOH605
A	HOH631

---

site_id	AC9
Number of Residues	9
Details	binding site for residue K A 509

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	CA502
A	MG503
A	DTP507
P	DT8
P	DA9
P	HOH212

---

site_id	AD1
Number of Residues	6
Details	binding site for residue MG P 101

Chain	Residue
A	DTP507
A	DPO508
A	HOH645
A	HOH668
P	DA9
P	HOH225

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---