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5KFR

Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mn2+ for 600s

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue MN A 501
ChainResidue
AASP13
AASP115
AGLU116
AMN502
ASTP506
PDT8
PAS9
PHOH107

site_idAC2
Number of Residues7
Detailsbinding site for residue MN A 502
ChainResidue
AMET14
AASP115
AMN501
ASTP506
ADPO507
PAS9
AASP13

site_idAC3
Number of Residues10
Detailsbinding site for residue GOL A 503
ChainResidue
AARG24
AGLN25
APRO244
APHE247
ASER248
AGLY276
AGLU277
AHOH638
AHOH670
AHOH792

site_idAC4
Number of Residues7
Detailsbinding site for residue GOL A 504
ChainResidue
AGLU94
AALA95
AGLU98
AHOH682
AHOH714
AHOH715
AHOH860

site_idAC5
Number of Residues10
Detailsbinding site for residue GOL A 505
ChainResidue
AASN26
AHIS28
AGLY271
AILE272
AGLU273
ATYR274
AGLU277
AHOH611
AHOH617
AHOH738

site_idAC6
Number of Residues29
Detailsbinding site for residue STP A 506
ChainResidue
AASP13
AMET14
AASP15
ACYS16
APHE17
APHE18
AILE48
AALA49
ATYR52
AARG55
AARG61
AASP115
ALYS231
AMN501
AMN502
ADPO507
AHOH601
AHOH621
AHOH632
AHOH662
AHOH735
AHOH802
PDT8
PAS9
PHOH102
PHOH107
TDT3
TDT4
TDA5

site_idAC7
Number of Residues17
Detailsbinding site for residue DPO A 507
ChainResidue
AASP13
AMET14
AASP15
ACYS16
APHE17
ATYR52
AARG55
AARG61
AASP115
ALYS231
AMN502
ASTP506
AHOH621
AHOH632
AHOH662
AHOH735
PAS9

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO
ChainResidueDetails
AASP13
AMET14
AASP115
AGLU116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197
ChainResidueDetails
AARG61

226707

PDB entries from 2024-10-30

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