5KFA

Human DNA polymerase eta-DNA ternary complex: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 501

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	DTP505
A	K506

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site_id	AC2
Number of Residues	10
Details	binding site for residue GOL A 502

Chain	Residue
A	GLY276
A	GLU277
A	HOH709
A	HOH735
A	HOH749
A	HOH764
A	ARG24
A	PRO244
A	PHE247
A	SER248

---

site_id	AC3
Number of Residues	9
Details	binding site for residue GOL A 503

Chain	Residue
A	GLU94
A	ALA95
A	GLU98
A	ARG303
A	HOH623
A	HOH626
A	HOH646
A	HOH676
A	HOH861

---

site_id	AC4
Number of Residues	10
Details	binding site for residue GOL A 504

Chain	Residue
A	ASN26
A	PRO27
A	HIS28
A	GLY271
A	GLU273
A	TYR274
A	GLU277
A	HOH624
A	HOH625
A	HOH640

---

site_id	AC5
Number of Residues	27
Details	binding site for residue DTP A 505

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	CA501
A	K506
A	HOH670
A	HOH701
A	HOH704
A	HOH706
A	HOH714
A	HOH779
A	HOH828
P	DT8
P	HOH102
T	DT3
T	DT4
T	DA5

---

site_id	AC6
Number of Residues	6
Details	binding site for residue K A 506

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	CA501
A	DTP505
P	DT8

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO

Chain	Residue	Details
A	ASP13
A	MET14
A	ASP115
A	GLU116

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197

Chain	Residue	Details
A	ARG61

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