Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004032 | molecular_function | aldose reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004032 | molecular_function | aldose reductase (NADPH) activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue NAP A 400 |
| Chain | Residue |
| A | GLY22 |
| A | GLN188 |
| A | TYR214 |
| A | ALA215 |
| A | PRO216 |
| A | ILE217 |
| A | GLY218 |
| A | SER219 |
| A | PRO220 |
| A | ALA259 |
| A | ILE274 |
| A | THR23 |
| A | PRO275 |
| A | LYS276 |
| A | SER277 |
| A | THR278 |
| A | ASN279 |
| A | ARG282 |
| A | GLU285 |
| A | ASN286 |
| A | PHE314 |
| A | TRP24 |
| A | ASP47 |
| A | TYR52 |
| A | LYS81 |
| A | HIS114 |
| A | SER166 |
| A | ASN167 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | binding site for residue NAP B 400 |
| Chain | Residue |
| B | GLY22 |
| B | THR23 |
| B | TRP24 |
| B | ASP47 |
| B | TYR52 |
| B | LYS81 |
| B | HIS114 |
| B | SER166 |
| B | ASN167 |
| B | GLN188 |
| B | TYR214 |
| B | ALA215 |
| B | PRO216 |
| B | ILE217 |
| B | GLY218 |
| B | SER219 |
| B | PRO220 |
| B | ALA259 |
| B | ILE274 |
| B | LYS276 |
| B | SER277 |
| B | THR278 |
| B | ARG282 |
| B | GLU285 |
| B | ASN286 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. MeaqvdagrTRSVGLSNF |
| Chain | Residue | Details |
| A | MET151-PHE168 | |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. IPKSTNagRIkENfQV |
| Chain | Residue | Details |
| A | ILE274-VAL289 | |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRHIDTAfmyqnEaaIG |
| Chain | Residue | Details |
| A | GLY42-GLY59 | |
