5KEJ
Crystallographic structure of the Tau class glutathione S-transferase MiGSTU in complex with S-hexyl-glutathione
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004364 | molecular_function | glutathione transferase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006749 | biological_process | glutathione metabolic process |
A | 0009407 | biological_process | toxin catabolic process |
A | 0009636 | biological_process | response to toxic substance |
A | 0016740 | molecular_function | transferase activity |
B | 0004364 | molecular_function | glutathione transferase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006749 | biological_process | glutathione metabolic process |
B | 0009407 | biological_process | toxin catabolic process |
B | 0009636 | biological_process | response to toxic substance |
B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 12 |
Details | binding site for residue GTX A 301 |
Chain | Residue |
A | SER14 |
A | HOH425 |
A | HOH430 |
A | HOH434 |
A | TYR16 |
A | LYS53 |
A | LYS54 |
A | ILE55 |
A | GLU67 |
A | SER68 |
A | TYR108 |
A | HOH415 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue PEG A 302 |
Chain | Residue |
A | HIS73 |
A | HOH401 |
A | HOH433 |
B | HIS73 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue PEG A 303 |
Chain | Residue |
A | PRO188 |
A | HIS189 |
A | LYS192 |
B | SER80 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue PEG A 304 |
Chain | Residue |
A | LYS47 |
A | SER48 |
A | ASP62 |
site_id | AC5 |
Number of Residues | 10 |
Details | binding site for residue PEG A 305 |
Chain | Residue |
A | ILE85 |
A | PRO87 |
A | ASP92 |
A | ALA96 |
A | LEU144 |
A | PHE151 |
A | GLY152 |
A | GLY157 |
A | TYR158 |
A | LEU159 |
site_id | AC6 |
Number of Residues | 13 |
Details | binding site for residue GTX B 301 |
Chain | Residue |
B | SER14 |
B | PRO15 |
B | TYR16 |
B | LYS41 |
B | LYS54 |
B | ILE55 |
B | PRO56 |
B | GLU67 |
B | SER68 |
B | TYR108 |
B | HOH414 |
B | HOH424 |
B | HOH430 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue PEG B 302 |
Chain | Residue |
A | CYS66 |
B | ILE95 |
B | PHE98 |
B | TRP99 |
site_id | AC8 |
Number of Residues | 9 |
Details | binding site for residue PEG B 303 |
Chain | Residue |
B | SER84 |
B | ILE85 |
B | PRO87 |
B | PHE151 |
B | GLY152 |
B | ILE156 |
B | GLY157 |
B | TYR158 |
B | LEU159 |