5KEJ
Crystallographic structure of the Tau class glutathione S-transferase MiGSTU in complex with S-hexyl-glutathione
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009407 | biological_process | toxin catabolic process |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0016740 | molecular_function | transferase activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009407 | biological_process | toxin catabolic process |
| B | 0009636 | biological_process | response to toxic substance |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue GTX A 301 |
| Chain | Residue |
| A | SER14 |
| A | HOH425 |
| A | HOH430 |
| A | HOH434 |
| A | TYR16 |
| A | LYS53 |
| A | LYS54 |
| A | ILE55 |
| A | GLU67 |
| A | SER68 |
| A | TYR108 |
| A | HOH415 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 302 |
| Chain | Residue |
| A | HIS73 |
| A | HOH401 |
| A | HOH433 |
| B | HIS73 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 303 |
| Chain | Residue |
| A | PRO188 |
| A | HIS189 |
| A | LYS192 |
| B | SER80 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 304 |
| Chain | Residue |
| A | LYS47 |
| A | SER48 |
| A | ASP62 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue PEG A 305 |
| Chain | Residue |
| A | ILE85 |
| A | PRO87 |
| A | ASP92 |
| A | ALA96 |
| A | LEU144 |
| A | PHE151 |
| A | GLY152 |
| A | GLY157 |
| A | TYR158 |
| A | LEU159 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue GTX B 301 |
| Chain | Residue |
| B | SER14 |
| B | PRO15 |
| B | TYR16 |
| B | LYS41 |
| B | LYS54 |
| B | ILE55 |
| B | PRO56 |
| B | GLU67 |
| B | SER68 |
| B | TYR108 |
| B | HOH414 |
| B | HOH424 |
| B | HOH430 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 302 |
| Chain | Residue |
| A | CYS66 |
| B | ILE95 |
| B | PHE98 |
| B | TRP99 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue PEG B 303 |
| Chain | Residue |
| B | SER84 |
| B | ILE85 |
| B | PRO87 |
| B | PHE151 |
| B | GLY152 |
| B | ILE156 |
| B | GLY157 |
| B | TYR158 |
| B | LEU159 |
