5KC6

Crystal structure of Cbln1 (Val55-Gly58 deletion mutant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0007157	biological_process	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
A	0007268	biological_process	chemical synaptic transmission
A	0007399	biological_process	nervous system development
A	0007416	biological_process	synapse assembly
A	0009306	biological_process	protein secretion
A	0016020	cellular_component	membrane
A	0021707	biological_process	cerebellar granule cell differentiation
A	0031012	cellular_component	extracellular matrix
A	0042802	molecular_function	identical protein binding
A	0043083	cellular_component	synaptic cleft
A	0045202	cellular_component	synapse
A	0045211	cellular_component	postsynaptic membrane
A	0050808	biological_process	synapse organization
A	0051649	biological_process	establishment of localization in cell
A	0051965	biological_process	positive regulation of synapse assembly
A	0090394	biological_process	negative regulation of excitatory postsynaptic potential
A	0098688	cellular_component	parallel fiber to Purkinje cell synapse
A	0098820	cellular_component	trans-synaptic protein complex
A	0098978	cellular_component	glutamatergic synapse
A	0099151	biological_process	regulation of postsynaptic density assembly
A	0099550	biological_process	trans-synaptic signaling, modulating synaptic transmission
A	0099558	biological_process	maintenance of synapse structure
A	1900454	biological_process	positive regulation of long-term synaptic depression
A	1905606	biological_process	regulation of presynapse assembly
A	1905703	biological_process	negative regulation of inhibitory synapse assembly
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005886	cellular_component	plasma membrane
B	0007157	biological_process	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
B	0007268	biological_process	chemical synaptic transmission
B	0007399	biological_process	nervous system development
B	0007416	biological_process	synapse assembly
B	0009306	biological_process	protein secretion
B	0016020	cellular_component	membrane
B	0021707	biological_process	cerebellar granule cell differentiation
B	0031012	cellular_component	extracellular matrix
B	0042802	molecular_function	identical protein binding
B	0043083	cellular_component	synaptic cleft
B	0045202	cellular_component	synapse
B	0045211	cellular_component	postsynaptic membrane
B	0050808	biological_process	synapse organization
B	0051649	biological_process	establishment of localization in cell
B	0051965	biological_process	positive regulation of synapse assembly
B	0090394	biological_process	negative regulation of excitatory postsynaptic potential
B	0098688	cellular_component	parallel fiber to Purkinje cell synapse
B	0098820	cellular_component	trans-synaptic protein complex
B	0098978	cellular_component	glutamatergic synapse
B	0099151	biological_process	regulation of postsynaptic density assembly
B	0099550	biological_process	trans-synaptic signaling, modulating synaptic transmission
B	0099558	biological_process	maintenance of synapse structure
B	1900454	biological_process	positive regulation of long-term synaptic depression
B	1905606	biological_process	regulation of presynapse assembly
B	1905703	biological_process	negative regulation of inhibitory synapse assembly
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005886	cellular_component	plasma membrane
C	0007157	biological_process	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
C	0007268	biological_process	chemical synaptic transmission
C	0007399	biological_process	nervous system development
C	0007416	biological_process	synapse assembly
C	0009306	biological_process	protein secretion
C	0016020	cellular_component	membrane
C	0021707	biological_process	cerebellar granule cell differentiation
C	0031012	cellular_component	extracellular matrix
C	0042802	molecular_function	identical protein binding
C	0043083	cellular_component	synaptic cleft
C	0045202	cellular_component	synapse
C	0045211	cellular_component	postsynaptic membrane
C	0050808	biological_process	synapse organization
C	0051649	biological_process	establishment of localization in cell
C	0051965	biological_process	positive regulation of synapse assembly
C	0090394	biological_process	negative regulation of excitatory postsynaptic potential
C	0098688	cellular_component	parallel fiber to Purkinje cell synapse
C	0098820	cellular_component	trans-synaptic protein complex
C	0098978	cellular_component	glutamatergic synapse
C	0099151	biological_process	regulation of postsynaptic density assembly
C	0099550	biological_process	trans-synaptic signaling, modulating synaptic transmission
C	0099558	biological_process	maintenance of synapse structure
C	1900454	biological_process	positive regulation of long-term synaptic depression
C	1905606	biological_process	regulation of presynapse assembly
C	1905703	biological_process	negative regulation of inhibitory synapse assembly

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	393
Details	Region: {"description":"Necessary for interaction with CBLN3, and homotrimerization","evidences":[{"source":"UniProtKB","id":"Q9R171","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	75
Details	Region: {"description":"Essential for interaction with GRID2","evidences":[{"source":"PubMed","id":"27418511","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"27418511","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KC6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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