Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue GDG A 501 |
| Chain | Residue |
| A | TRP99 |
| A | ARG365 |
| A | LEU368 |
| A | ASP385 |
| A | GLY386 |
| A | MET387 |
| A | ASN388 |
| A | LEU389 |
| A | GLU393 |
| A | HOH639 |
| A | HOH713 |
| A | HIS168 |
| A | HIS199 |
| A | ILE247 |
| A | ARG286 |
| A | LYS291 |
| A | THR321 |
| A | PRO362 |
| A | VAL363 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue NHE A 502 |
| Chain | Residue |
| A | GLU175 |
| A | MET178 |
| A | ARG183 |
| A | ARG213 |
| A | ARG384 |
| A | GLU409 |
| A | PHE410 |
| A | EDO508 |
| A | HOH708 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | GLN298 |
| A | ALA301 |
| A | ARG339 |
| A | GLN340 |
| A | HIS343 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ALA258 |
| A | ARG264 |
| A | CYS397 |
| A | SER399 |
| A | ASP400 |
| A | HOH617 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | HIS357 |
| A | TYR358 |
| A | LEU359 |
| A | HOH601 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | ARG213 |
| A | LEU214 |
| A | GLU444 |
| A | ARG447 |
| A | ARG448 |
| A | ARG451 |
| A | HOH763 |
| A | HOH789 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLU185 |
| A | HOH796 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | LEU200 |
| A | ARG213 |
| A | GLU409 |
| A | THR411 |
| A | NHE502 |
| A | HOH675 |
| A | HOH708 |
| A | HOH800 |
