5K0P
Crystal structure of the archaeosine synthase QueF-Like in the apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008616 | biological_process | queuosine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0033739 | molecular_function | preQ1 synthase activity |
| B | 0008033 | biological_process | tRNA processing |
| B | 0008616 | biological_process | queuosine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0033739 | molecular_function | preQ1 synthase activity |
| C | 0008033 | biological_process | tRNA processing |
| C | 0008616 | biological_process | queuosine biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0033739 | molecular_function | preQ1 synthase activity |
| D | 0008033 | biological_process | tRNA processing |
| D | 0008616 | biological_process | queuosine biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0033739 | molecular_function | preQ1 synthase activity |
| E | 0008033 | biological_process | tRNA processing |
| E | 0008616 | biological_process | queuosine biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0033739 | molecular_function | preQ1 synthase activity |
| F | 0008033 | biological_process | tRNA processing |
| F | 0008616 | biological_process | queuosine biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0033739 | molecular_function | preQ1 synthase activity |
| G | 0008033 | biological_process | tRNA processing |
| G | 0008616 | biological_process | queuosine biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0033739 | molecular_function | preQ1 synthase activity |
| H | 0008033 | biological_process | tRNA processing |
| H | 0008616 | biological_process | queuosine biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0033739 | molecular_function | preQ1 synthase activity |
| I | 0008033 | biological_process | tRNA processing |
| I | 0008616 | biological_process | queuosine biosynthetic process |
| I | 0016740 | molecular_function | transferase activity |
| I | 0033739 | molecular_function | preQ1 synthase activity |
| J | 0008033 | biological_process | tRNA processing |
| J | 0008616 | biological_process | queuosine biosynthetic process |
| J | 0016740 | molecular_function | transferase activity |
| J | 0033739 | molecular_function | preQ1 synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SCN A 201 |
| Chain | Residue |
| A | PRO22 |
| A | ASP28 |
| A | TYR90 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SCN B 201 |
| Chain | Residue |
| B | ASP28 |
| B | HIS62 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue PGE C 201 |
| Chain | Residue |
| C | TYR89 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SCN C 202 |
| Chain | Residue |
| C | PRO22 |
| C | TYR90 |
| C | HOH330 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue PGE D 201 |
| Chain | Residue |
| D | TYR89 |
| D | GLU94 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SCN D 202 |
| Chain | Residue |
| D | PRO22 |
| D | ASP28 |
| D | TYR90 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SCN E 201 |
| Chain | Residue |
| E | ASP28 |
| E | TYR90 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue PGE F 201 |
| Chain | Residue |
| F | ARG16 |
| G | GLU94 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SCN F 202 |
| Chain | Residue |
| F | PRO22 |
| F | ASP28 |
| F | HIS62 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SCN G 201 |
| Chain | Residue |
| G | ASP28 |
| G | TYR90 |
| G | HOH321 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SCN H 201 |
| Chain | Residue |
| H | PRO22 |
| H | ILE23 |
| H | ASP28 |
| H | TYR90 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 I 201 |
| Chain | Residue |
| I | ARG16 |
| I | LYS87 |
| I | HOH316 |
| I | HOH337 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SCN I 202 |
| Chain | Residue |
| I | ASP28 |
| I | LEU61 |
| I | HOH310 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SCN J 201 |
| Chain | Residue |
| J | ASP28 |
| J | LEU61 |
| J | HOH312 |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. AAVNPPY |
| Chain | Residue | Details |
| A | ALA75-TYR81 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | ACT_SITE: Thioimide intermediate => ECO:0000269|PubMed:27802572, ECO:0000269|PubMed:28383498 |
| Chain | Residue | Details |
| A | CYS21 | |
| B | CYS21 | |
| C | CYS21 | |
| D | CYS21 | |
| E | CYS21 | |
| F | CYS21 | |
| G | CYS21 | |
| H | CYS21 | |
| I | CYS21 | |
| J | CYS21 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:27802572 |
| Chain | Residue | Details |
| A | ASP28 | |
| B | ASP28 | |
| C | ASP28 | |
| D | ASP28 | |
| E | ASP28 | |
| F | ASP28 | |
| G | ASP28 | |
| H | ASP28 | |
| I | ASP28 | |
| J | ASP28 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | BINDING: in other chain => ECO:0000269|PubMed:27802572 |
| Chain | Residue | Details |
| F | ASP28 | |
| F | HIS62 | |
| G | ASP28 | |
| G | HIS62 | |
| H | ASP28 | |
| H | HIS62 | |
| I | ASP28 | |
| I | HIS62 | |
| J | ASP28 | |
| J | HIS62 | |
| A | ASP28 | |
| A | HIS62 | |
| B | ASP28 | |
| B | HIS62 | |
| C | ASP28 | |
| C | HIS62 | |
| D | ASP28 | |
| D | HIS62 | |
| E | ASP28 | |
| E | HIS62 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27802572 |
| Chain | Residue | Details |
| A | LEU43 | |
| B | LEU43 | |
| C | LEU43 | |
| D | LEU43 | |
| E | LEU43 | |
| F | LEU43 | |
| G | LEU43 | |
| H | LEU43 | |
| I | LEU43 | |
| J | LEU43 |
