5K0A
Structure of an oxidoreductase from Synechocystis sp. PCC6803
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0045454 | biological_process | cell redox homeostasis |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0045454 | biological_process | cell redox homeostasis |
| D | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 40 |
| Details | binding site for residue FAD A 401 |
| Chain | Residue |
| A | GLY26 |
| A | SER55 |
| A | TRP57 |
| A | MET58 |
| A | ASP60 |
| A | LEU61 |
| A | ARG62 |
| A | ASN63 |
| A | GLY94 |
| A | TYR95 |
| A | VAL96 |
| A | GLY28 |
| A | ALA130 |
| A | THR131 |
| A | GLY151 |
| A | VAL156 |
| A | CYS160 |
| A | HIS258 |
| A | GLY292 |
| A | ASP293 |
| A | ASN299 |
| A | GLN300 |
| A | MET29 |
| A | VAL301 |
| A | ALA304 |
| A | NO3404 |
| A | HOH552 |
| A | HOH576 |
| A | HOH581 |
| A | HOH584 |
| A | HOH609 |
| A | HOH630 |
| A | HOH636 |
| A | GLY30 |
| A | HOH698 |
| A | GLU49 |
| A | LYS50 |
| A | GLY51 |
| A | GLY53 |
| A | ARG54 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue FAD A 402 |
| Chain | Residue |
| A | LYS50 |
| A | ARG52 |
| A | TRP57 |
| A | TYR95 |
| A | LYS111 |
| A | GLY113 |
| A | LYS114 |
| A | LEU137 |
| A | TYR147 |
| A | ALA150 |
| A | HOH512 |
| A | HOH537 |
| A | HOH545 |
| A | HOH554 |
| A | HOH559 |
| A | HOH566 |
| A | HOH580 |
| A | HOH691 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue NO3 A 403 |
| Chain | Residue |
| A | GLY254 |
| A | SER255 |
| A | TYR257 |
| A | HOH528 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 A 404 |
| Chain | Residue |
| A | TYR95 |
| A | HIS258 |
| A | ASN259 |
| A | HIS260 |
| A | FAD401 |
| A | HOH501 |
| A | HOH595 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue PG4 A 405 |
| Chain | Residue |
| A | ASN278 |
| A | ASP279 |
| A | GLN282 |
| A | THR283 |
| A | SER284 |
| A | HOH504 |
| B | PG4407 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 A 406 |
| Chain | Residue |
| A | ASN181 |
| A | PHE184 |
| A | GLU206 |
| A | LYS210 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue NO3 A 407 |
| Chain | Residue |
| A | ARG62 |
| B | HIS86 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 A 408 |
| Chain | Residue |
| A | HIS86 |
| A | HOH503 |
| B | ARG62 |
| site_id | AC9 |
| Number of Residues | 40 |
| Details | binding site for residue FAD B 401 |
| Chain | Residue |
| B | LEU61 |
| B | ARG62 |
| B | ASN63 |
| B | GLY94 |
| B | TYR95 |
| B | VAL96 |
| B | ALA130 |
| B | THR131 |
| B | GLY151 |
| B | VAL156 |
| B | CYS160 |
| B | HIS258 |
| B | GLY292 |
| B | ASP293 |
| B | ASN299 |
| B | GLN300 |
| B | VAL301 |
| B | ALA304 |
| B | HOH535 |
| B | HOH566 |
| B | HOH595 |
| B | HOH596 |
| B | HOH602 |
| B | HOH614 |
| B | HOH649 |
| B | HOH666 |
| A | HOH614 |
| B | GLY26 |
| B | GLY28 |
| B | MET29 |
| B | GLY30 |
| B | GLU49 |
| B | LYS50 |
| B | GLY51 |
| B | GLY53 |
| B | ARG54 |
| B | SER55 |
| B | TRP57 |
| B | MET58 |
| B | ASP60 |
| site_id | AD1 |
| Number of Residues | 17 |
| Details | binding site for residue FAD B 402 |
| Chain | Residue |
| B | LYS50 |
| B | TRP57 |
| B | TYR95 |
| B | LYS111 |
| B | GLY113 |
| B | LYS114 |
| B | LEU137 |
| B | TYR147 |
| B | HOH511 |
| B | HOH546 |
| B | HOH554 |
| B | HOH557 |
| B | HOH585 |
| B | HOH632 |
| B | HOH680 |
| B | HOH686 |
| B | HOH688 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 B 403 |
| Chain | Residue |
| B | HIS86 |
| B | HOH551 |
| D | ARG74 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE B 404 |
| Chain | Residue |
| B | ASP98 |
| B | LYS109 |
| B | TYR119 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 B 405 |
| Chain | Residue |
| B | TYR126 |
| B | ARG287 |
| B | HOH501 |
| B | HOH542 |
| B | HOH569 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue PG4 B 406 |
| Chain | Residue |
| B | ASN181 |
| B | PHE184 |
| B | MET207 |
| B | LYS210 |
| B | HOH505 |
| B | HOH618 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 B 407 |
| Chain | Residue |
| A | PG4405 |
| B | ASN278 |
| B | ASP279 |
| B | GLN282 |
| B | THR283 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 B 408 |
| Chain | Residue |
| B | GLU177 |
| B | GLY204 |
| B | ASP205 |
| B | GLU206 |
| B | HOH504 |
| B | HOH538 |
| B | HOH559 |
| B | HOH613 |
| B | HOH689 |
| site_id | AD8 |
| Number of Residues | 40 |
| Details | binding site for residue FAD C 401 |
| Chain | Residue |
| C | GLY26 |
| C | GLY28 |
| C | MET29 |
| C | GLY30 |
| C | GLU49 |
| C | LYS50 |
| C | GLY51 |
| C | GLY53 |
| C | ARG54 |
| C | SER55 |
| C | TRP57 |
| C | MET58 |
| C | ASP60 |
| C | LEU61 |
| C | ARG62 |
| C | ASN63 |
| C | GLY94 |
| C | TYR95 |
| C | VAL96 |
| C | ALA130 |
| C | THR131 |
| C | GLY151 |
| C | VAL156 |
| C | CYS160 |
| C | HIS258 |
| C | GLY292 |
| C | ASP293 |
| C | ASN299 |
| C | GLN300 |
| C | VAL301 |
| C | ALA304 |
| C | HOH515 |
| C | HOH526 |
| C | HOH576 |
| C | HOH579 |
| C | HOH585 |
| C | HOH591 |
| C | HOH612 |
| C | HOH623 |
| D | HOH666 |
| site_id | AD9 |
| Number of Residues | 18 |
| Details | binding site for residue FAD C 402 |
| Chain | Residue |
| C | LYS50 |
| C | ARG52 |
| C | TRP57 |
| C | TYR95 |
| C | LYS111 |
| C | GLY113 |
| C | LEU137 |
| C | TYR147 |
| C | HOH507 |
| C | HOH519 |
| C | HOH530 |
| C | HOH545 |
| C | HOH563 |
| C | HOH580 |
| C | HOH601 |
| C | HOH614 |
| C | HOH651 |
| D | LYS115 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue PG4 C 403 |
| Chain | Residue |
| C | ASN278 |
| C | ASP279 |
| C | GLN282 |
| C | THR283 |
| C | SER284 |
| C | HOH501 |
| D | PG4406 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue NO3 C 404 |
| Chain | Residue |
| C | TYR126 |
| C | ARG287 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE C 405 |
| Chain | Residue |
| C | ASP98 |
| C | LYS109 |
| C | TYR119 |
| C | ILE121 |
| D | GLN139 |
| D | LEU140 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE C 406 |
| Chain | Residue |
| C | ASN181 |
| C | PHE184 |
| C | GLU206 |
| C | MET207 |
| C | LYS210 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue 1PE D 401 |
| Chain | Residue |
| C | PHE163 |
| C | TRP166 |
| D | GLY42 |
| D | LEU43 |
| D | GLY88 |
| D | HOH509 |
| D | HOH752 |
| site_id | AE6 |
| Number of Residues | 40 |
| Details | binding site for residue FAD D 402 |
| Chain | Residue |
| D | GLY26 |
| D | GLY28 |
| D | MET29 |
| D | GLY30 |
| D | GLU49 |
| D | LYS50 |
| D | GLY51 |
| D | GLY53 |
| D | ARG54 |
| D | SER55 |
| D | TRP57 |
| D | MET58 |
| D | ASP60 |
| D | LEU61 |
| D | ARG62 |
| D | ASN63 |
| D | GLY94 |
| D | TYR95 |
| D | VAL96 |
| D | ALA130 |
| D | THR131 |
| D | GLY151 |
| D | VAL156 |
| D | CYS160 |
| D | HIS258 |
| D | GLY292 |
| D | ASP293 |
| D | ASN299 |
| D | GLN300 |
| D | VAL301 |
| D | ALA304 |
| D | HOH548 |
| D | HOH555 |
| D | HOH587 |
| D | HOH624 |
| D | HOH641 |
| D | HOH647 |
| D | HOH688 |
| D | HOH712 |
| D | HOH735 |
| site_id | AE7 |
| Number of Residues | 20 |
| Details | binding site for residue FAD D 403 |
| Chain | Residue |
| D | LYS50 |
| D | ARG52 |
| D | TRP57 |
| D | TYR95 |
| D | LYS111 |
| D | GLY113 |
| D | LYS114 |
| D | LEU137 |
| D | TYR147 |
| D | HOH502 |
| D | HOH519 |
| D | HOH532 |
| D | HOH566 |
| D | HOH569 |
| D | HOH576 |
| D | HOH598 |
| D | HOH614 |
| D | HOH650 |
| D | HOH669 |
| D | HOH753 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 D 404 |
| Chain | Residue |
| D | GLY204 |
| D | ASP205 |
| D | GLU206 |
| D | HOH539 |
| D | HOH545 |
| D | HOH673 |
| D | HOH714 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue NO3 D 405 |
| Chain | Residue |
| D | ARG54 |
| D | VAL156 |
| D | CSO157 |
| D | ASN299 |
| D | HOH689 |
| D | HOH741 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue PG4 D 406 |
| Chain | Residue |
| C | PG4403 |
| D | ASN278 |
| D | ASP279 |
| D | GLN282 |
| D | THR283 |
| D | SER284 |
| D | HOH774 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE D 407 |
| Chain | Residue |
| D | ASP98 |
| D | LYS109 |
| D | TYR119 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue PGE D 408 |
| Chain | Residue |
| D | ASN181 |
| D | PHE184 |
| D | GLU206 |
| D | MET207 |
| D | LYS210 |
