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5JZW

Cryo-EM structures of aerolysin post-prepore and quasipore

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0016020cellular_componentmembrane
A0020002cellular_componenthost cell plasma membrane
A0035821biological_processmodulation of process of another organism
A0042802molecular_functionidentical protein binding
A0090729molecular_functiontoxin activity
B0005576cellular_componentextracellular region
B0016020cellular_componentmembrane
B0020002cellular_componenthost cell plasma membrane
B0035821biological_processmodulation of process of another organism
B0042802molecular_functionidentical protein binding
B0090729molecular_functiontoxin activity
C0005576cellular_componentextracellular region
C0016020cellular_componentmembrane
C0020002cellular_componenthost cell plasma membrane
C0035821biological_processmodulation of process of another organism
C0042802molecular_functionidentical protein binding
C0090729molecular_functiontoxin activity
D0005576cellular_componentextracellular region
D0016020cellular_componentmembrane
D0020002cellular_componenthost cell plasma membrane
D0035821biological_processmodulation of process of another organism
D0042802molecular_functionidentical protein binding
D0090729molecular_functiontoxin activity
E0005576cellular_componentextracellular region
E0016020cellular_componentmembrane
E0020002cellular_componenthost cell plasma membrane
E0035821biological_processmodulation of process of another organism
E0042802molecular_functionidentical protein binding
E0090729molecular_functiontoxin activity
F0005576cellular_componentextracellular region
F0016020cellular_componentmembrane
F0020002cellular_componenthost cell plasma membrane
F0035821biological_processmodulation of process of another organism
F0042802molecular_functionidentical protein binding
F0090729molecular_functiontoxin activity
G0005576cellular_componentextracellular region
G0016020cellular_componentmembrane
G0020002cellular_componenthost cell plasma membrane
G0035821biological_processmodulation of process of another organism
G0042802molecular_functionidentical protein binding
G0090729molecular_functiontoxin activity
H0005576cellular_componentextracellular region
H0016020cellular_componentmembrane
H0020002cellular_componenthost cell plasma membrane
H0035821biological_processmodulation of process of another organism
H0042802molecular_functionidentical protein binding
H0090729molecular_functiontoxin activity
I0005576cellular_componentextracellular region
I0016020cellular_componentmembrane
I0020002cellular_componenthost cell plasma membrane
I0035821biological_processmodulation of process of another organism
I0042802molecular_functionidentical protein binding
I0090729molecular_functiontoxin activity
J0005576cellular_componentextracellular region
J0016020cellular_componentmembrane
J0020002cellular_componenthost cell plasma membrane
J0035821biological_processmodulation of process of another organism
J0042802molecular_functionidentical protein binding
J0090729molecular_functiontoxin activity
K0005576cellular_componentextracellular region
K0016020cellular_componentmembrane
K0020002cellular_componenthost cell plasma membrane
K0035821biological_processmodulation of process of another organism
K0042802molecular_functionidentical protein binding
K0090729molecular_functiontoxin activity
L0005576cellular_componentextracellular region
L0016020cellular_componentmembrane
L0020002cellular_componenthost cell plasma membrane
L0035821biological_processmodulation of process of another organism
L0042802molecular_functionidentical protein binding
L0090729molecular_functiontoxin activity
M0005576cellular_componentextracellular region
M0016020cellular_componentmembrane
M0020002cellular_componenthost cell plasma membrane
M0035821biological_processmodulation of process of another organism
M0042802molecular_functionidentical protein binding
M0090729molecular_functiontoxin activity
N0005576cellular_componentextracellular region
N0016020cellular_componentmembrane
N0020002cellular_componenthost cell plasma membrane
N0035821biological_processmodulation of process of another organism
N0042802molecular_functionidentical protein binding
N0090729molecular_functiontoxin activity
Functional Information from PROSITE/UniProt
site_idPS00274
Number of Residues10
DetailsAEROLYSIN Aerolysin type toxins signature. TatNWskTNT
ChainResidueDetails
ATHR223-THR232

site_idPS00387
Number of Residues7
DetailsPPASE Inorganic pyrophosphatase signature. DGDEVDV
ChainResidueDetails
AASP95-VAL101

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsSITE: Important for oligomerization
ChainResidueDetails
AHIS132
JHIS132
KHIS132
LHIS132
MHIS132
NHIS132
BHIS132
CHIS132
DHIS132
EHIS132
FHIS132
GHIS132
HHIS132
IHIS132

site_idSWS_FT_FI2
Number of Residues28
DetailsSITE: Important for heptamerization
ChainResidueDetails
ALYS351
EGLU367
FLYS351
FGLU367
GLYS351
GGLU367
HLYS351
HGLU367
ILYS351
IGLU367
JLYS351
AGLU367
JGLU367
KLYS351
KGLU367
LLYS351
LGLU367
MLYS351
MGLU367
NLYS351
NGLU367
BLYS351
BGLU367
CLYS351
CGLU367
DLYS351
DGLU367
ELYS351

227111

PDB entries from 2024-11-06

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