5JXX
Crystal structure of UDP-N-acetylglucosamine O-acyltransferase (LpxA) from Moraxella catarrhalis RH4.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| C | 0008610 | biological_process | lipid biosynthetic process |
| C | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| D | 0008610 | biological_process | lipid biosynthetic process |
| D | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| E | 0008610 | biological_process | lipid biosynthetic process |
| E | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| F | 0008610 | biological_process | lipid biosynthetic process |
| F | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| F | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | GLN68 |
| A | ALA119 |
| A | HIS120 |
| A | GLY138 |
| E | MET113 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue FLC A 302 |
| Chain | Residue |
| F | LYS29 |
| F | ASN30 |
| F | ASN48 |
| F | GLN76 |
| A | LYS188 |
| A | ALA189 |
| A | HIS190 |
| A | ARG219 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| B | HIS155 |
| B | ARG253 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 302 |
| Chain | Residue |
| B | ASP161 |
| B | LEU243 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue FLC B 303 |
| Chain | Residue |
| B | GLN68 |
| B | HIS117 |
| B | ALA119 |
| B | HIS120 |
| B | ALA137 |
| B | GLY138 |
| B | GLN156 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | GLN68 |
| C | ALA119 |
| C | HIS120 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 302 |
| Chain | Residue |
| C | HIS190 |
| C | ARG219 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| D | GLN68 |
| D | ALA119 |
| D | HIS120 |
| D | HOH403 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL D 302 |
| Chain | Residue |
| D | HIS36 |
| D | HIS54 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL D 303 |
| Chain | Residue |
| D | HIS54 |
| D | HIS84 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 301 |
| Chain | Residue |
| C | ASN132 |
| E | GLN68 |
| E | ALA119 |
| E | HIS120 |
| E | GLN156 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue GOL E 302 |
| Chain | Residue |
| E | HIS36 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 301 |
| Chain | Residue |
| B | ASN132 |
| F | GLN68 |
| F | HIS117 |
| F | ALA119 |
| F | HIS120 |
| F | ALA137 |
Functional Information from PROSITE/UniProt
| site_id | PS00101 |
| Number of Residues | 29 |
| Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IAdsAiIgpyCiVGknSqIGahTvLrshV |
| Chain | Residue | Details |
| A | ILE15-VAL43 | |
| A | ILE148-VAL176 |
