5JXP

Crystal structure of Porphyromonas endodontalis DPP11 in alternate conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0005576	cellular_component	extracellular region
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008236	molecular_function	serine-type peptidase activity
A	0008239	molecular_function	dipeptidyl-peptidase activity
A	0009986	cellular_component	cell surface
A	0016787	molecular_function	hydrolase activity
A	0043171	biological_process	peptide catabolic process
A	0070009	molecular_function	serine-type aminopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CA A 801

Chain	Residue
A	ASN632
A	ARG694

---

site_id	AC2
Number of Residues	4
Details	binding site for residue CL A 802

Chain	Residue
A	LEU598
A	GLU599
A	SER636
A	MET637

---

site_id	AC3
Number of Residues	2
Details	binding site for residue CL A 803

Chain	Residue
A	TYR530
A	LYS537

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"V5YM14","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"V5YM14","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"21896480","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Is essential for the Asp/Glu P1 specificity of DPP11; involved in the recognition of the Asp/Glu residue at the P1 position of substrate peptides","evidences":[{"source":"UniProtKB","id":"B2RID1","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"21896480","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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