5JQL

Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 2.9 Angstroms Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0006869	biological_process	lipid transport
A	0008289	molecular_function	lipid binding
A	0015914	biological_process	phospholipid transport
A	0032048	biological_process	cardiolipin metabolic process
A	0045332	biological_process	phospholipid translocation
A	0120009	biological_process	intermembrane lipid transfer
A	1990050	molecular_function	phosphatidic acid transfer activity
A	2001247	biological_process	positive regulation of phosphatidylcholine biosynthetic process
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005758	cellular_component	mitochondrial intermembrane space
B	0006869	biological_process	lipid transport
B	0007005	biological_process	mitochondrion organization
B	0015914	biological_process	phospholipid transport
B	0033108	biological_process	mitochondrial respiratory chain complex assembly
B	0045332	biological_process	phospholipid translocation
B	0120009	biological_process	intermembrane lipid transfer
B	1990050	molecular_function	phosphatidic acid transfer activity
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005758	cellular_component	mitochondrial intermembrane space
C	0006869	biological_process	lipid transport
C	0008289	molecular_function	lipid binding
C	0015914	biological_process	phospholipid transport
C	0032048	biological_process	cardiolipin metabolic process
C	0045332	biological_process	phospholipid translocation
C	0120009	biological_process	intermembrane lipid transfer
C	1990050	molecular_function	phosphatidic acid transfer activity
C	2001247	biological_process	positive regulation of phosphatidylcholine biosynthetic process
D	0003674	molecular_function	molecular_function
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005758	cellular_component	mitochondrial intermembrane space
D	0006869	biological_process	lipid transport
D	0007005	biological_process	mitochondrion organization
D	0015914	biological_process	phospholipid transport
D	0033108	biological_process	mitochondrial respiratory chain complex assembly
D	0045332	biological_process	phospholipid translocation
D	0120009	biological_process	intermembrane lipid transfer
D	1990050	molecular_function	phosphatidic acid transfer activity
E	0005515	molecular_function	protein binding
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005758	cellular_component	mitochondrial intermembrane space
E	0006869	biological_process	lipid transport
E	0008289	molecular_function	lipid binding
E	0015914	biological_process	phospholipid transport
E	0032048	biological_process	cardiolipin metabolic process
E	0045332	biological_process	phospholipid translocation
E	0120009	biological_process	intermembrane lipid transfer
E	1990050	molecular_function	phosphatidic acid transfer activity
E	2001247	biological_process	positive regulation of phosphatidylcholine biosynthetic process
F	0003674	molecular_function	molecular_function
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005758	cellular_component	mitochondrial intermembrane space
F	0006869	biological_process	lipid transport
F	0007005	biological_process	mitochondrion organization
F	0015914	biological_process	phospholipid transport
F	0033108	biological_process	mitochondrial respiratory chain complex assembly
F	0045332	biological_process	phospholipid translocation
F	0120009	biological_process	intermembrane lipid transfer
F	1990050	molecular_function	phosphatidic acid transfer activity
G	0005515	molecular_function	protein binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005758	cellular_component	mitochondrial intermembrane space
G	0006869	biological_process	lipid transport
G	0008289	molecular_function	lipid binding
G	0015914	biological_process	phospholipid transport
G	0032048	biological_process	cardiolipin metabolic process
G	0045332	biological_process	phospholipid translocation
G	0120009	biological_process	intermembrane lipid transfer
G	1990050	molecular_function	phosphatidic acid transfer activity
G	2001247	biological_process	positive regulation of phosphatidylcholine biosynthetic process
H	0003674	molecular_function	molecular_function
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005758	cellular_component	mitochondrial intermembrane space
H	0006869	biological_process	lipid transport
H	0007005	biological_process	mitochondrion organization
H	0015914	biological_process	phospholipid transport
H	0033108	biological_process	mitochondrial respiratory chain complex assembly
H	0045332	biological_process	phospholipid translocation
H	0120009	biological_process	intermembrane lipid transfer
H	1990050	molecular_function	phosphatidic acid transfer activity
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005758	cellular_component	mitochondrial intermembrane space
I	0006869	biological_process	lipid transport
I	0008289	molecular_function	lipid binding
I	0015914	biological_process	phospholipid transport
I	0032048	biological_process	cardiolipin metabolic process
I	0045332	biological_process	phospholipid translocation
I	0120009	biological_process	intermembrane lipid transfer
I	1990050	molecular_function	phosphatidic acid transfer activity
I	2001247	biological_process	positive regulation of phosphatidylcholine biosynthetic process
J	0003674	molecular_function	molecular_function
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005758	cellular_component	mitochondrial intermembrane space
J	0006869	biological_process	lipid transport
J	0007005	biological_process	mitochondrion organization
J	0015914	biological_process	phospholipid transport
J	0033108	biological_process	mitochondrial respiratory chain complex assembly
J	0045332	biological_process	phospholipid translocation
J	0120009	biological_process	intermembrane lipid transfer
J	1990050	molecular_function	phosphatidic acid transfer activity
K	0005515	molecular_function	protein binding
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005758	cellular_component	mitochondrial intermembrane space
K	0006869	biological_process	lipid transport
K	0008289	molecular_function	lipid binding
K	0015914	biological_process	phospholipid transport
K	0032048	biological_process	cardiolipin metabolic process
K	0045332	biological_process	phospholipid translocation
K	0120009	biological_process	intermembrane lipid transfer
K	1990050	molecular_function	phosphatidic acid transfer activity
K	2001247	biological_process	positive regulation of phosphatidylcholine biosynthetic process
L	0003674	molecular_function	molecular_function
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005758	cellular_component	mitochondrial intermembrane space
L	0006869	biological_process	lipid transport
L	0007005	biological_process	mitochondrion organization
L	0015914	biological_process	phospholipid transport
L	0033108	biological_process	mitochondrial respiratory chain complex assembly
L	0045332	biological_process	phospholipid translocation
L	0120009	biological_process	intermembrane lipid transfer
L	1990050	molecular_function	phosphatidic acid transfer activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:26235513

Chain	Residue	Details
G	TYR26
G	LYS58
E	TYR26
E	LYS58
I	TYR26
I	LYS58
K	TYR26
K	LYS58

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:26071601

Chain	Residue	Details
G	LYS148
E	LYS148
I	LYS148
K	LYS148

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:26071601, ECO:0000269|PubMed:26235513

Chain	Residue	Details
G	ASN152
E	ASN152
I	ASN152
K	ASN152

---