5JPQ

Cryo-EM structure of the 90S pre-ribosome

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003735	molecular_function	structural constituent of ribosome
0	0005840	cellular_component	ribosome
0	0006412	biological_process	translation
0	1990904	cellular_component	ribonucleoprotein complex
1	0000028	biological_process	ribosomal small subunit assembly
1	0000054	biological_process	ribosomal subunit export from nucleus
1	0003735	molecular_function	structural constituent of ribosome
1	0005515	molecular_function	protein binding
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	0022627	cellular_component	cytosolic small ribosomal subunit
1	0030490	biological_process	maturation of SSU-rRNA
1	1900153	biological_process	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
1	1990904	cellular_component	ribonucleoprotein complex
G	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G	0005730	cellular_component	nucleolus
G	0006364	biological_process	rRNA processing
G	0030515	molecular_function	snoRNA binding
G	0030686	cellular_component	90S preribosome
G	0032040	cellular_component	small-subunit processome
G	0034455	cellular_component	t-UTP complex
G	0042254	biological_process	ribosome biogenesis
G	0045943	biological_process	positive regulation of transcription by RNA polymerase I
G	1990904	cellular_component	ribonucleoprotein complex
I	0003674	molecular_function	molecular_function
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005730	cellular_component	nucleolus
I	0006364	biological_process	rRNA processing
I	0030490	biological_process	maturation of SSU-rRNA
I	0030686	cellular_component	90S preribosome
I	0032040	cellular_component	small-subunit processome
I	0034388	cellular_component	Pwp2p-containing subcomplex of 90S preribosome
I	0042254	biological_process	ribosome biogenesis
I	1990904	cellular_component	ribonucleoprotein complex
S	0030515	molecular_function	snoRNA binding
S	0031428	cellular_component	box C/D methylation guide snoRNP complex
S	0032040	cellular_component	small-subunit processome
S	1990904	cellular_component	ribonucleoprotein complex
T	0030515	molecular_function	snoRNA binding
T	0031428	cellular_component	box C/D methylation guide snoRNP complex
T	0032040	cellular_component	small-subunit processome
T	1990904	cellular_component	ribonucleoprotein complex
U	0001682	biological_process	tRNA 5'-leader removal
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0004526	molecular_function	ribonuclease P activity
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0008033	biological_process	tRNA processing
U	0019843	molecular_function	rRNA binding
U	0042254	biological_process	ribosome biogenesis
U	1990904	cellular_component	ribonucleoprotein complex
V	0001682	biological_process	tRNA 5'-leader removal
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0004526	molecular_function	ribonuclease P activity
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0008033	biological_process	tRNA processing
V	0019843	molecular_function	rRNA binding
V	0042254	biological_process	ribosome biogenesis
V	1990904	cellular_component	ribonucleoprotein complex
W	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
W	0003723	molecular_function	RNA binding
W	0005515	molecular_function	protein binding
W	0006338	biological_process	chromatin remodeling
W	0006364	biological_process	rRNA processing
W	0008033	biological_process	tRNA processing
W	0008168	molecular_function	methyltransferase activity
W	0008649	molecular_function	rRNA methyltransferase activity
W	0016740	molecular_function	transferase activity
W	0031167	biological_process	rRNA methylation
W	0032259	biological_process	methylation
W	1990259	molecular_function	histone H2AQ104 methyltransferase activity
X	0000494	biological_process	box C/D sno(s)RNA 3'-end processing
X	0003723	molecular_function	RNA binding
X	0005515	molecular_function	protein binding
X	0006338	biological_process	chromatin remodeling
X	0006364	biological_process	rRNA processing
X	0008033	biological_process	tRNA processing
X	0008168	molecular_function	methyltransferase activity
X	0008649	molecular_function	rRNA methyltransferase activity
X	0016740	molecular_function	transferase activity
X	0031167	biological_process	rRNA methylation
X	0032259	biological_process	methylation
X	1990259	molecular_function	histone H2AQ104 methyltransferase activity
Y	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Y	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Y	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Y	0005515	molecular_function	protein binding
Y	0005654	cellular_component	nucleoplasm
Y	0005730	cellular_component	nucleolus
Y	0006364	biological_process	rRNA processing
Y	0030490	biological_process	maturation of SSU-rRNA
Y	0030515	molecular_function	snoRNA binding
Y	0030686	cellular_component	90S preribosome
Y	0031428	cellular_component	box C/D methylation guide snoRNP complex
Y	0032040	cellular_component	small-subunit processome
Y	0034511	molecular_function	U3 snoRNA binding
Y	0042254	biological_process	ribosome biogenesis
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0003824	molecular_function	catalytic activity
Z	0003963	molecular_function	RNA-3'-phosphate cyclase activity
Z	0004521	molecular_function	RNA endonuclease activity
Z	0005515	molecular_function	protein binding
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0006364	biological_process	rRNA processing
Z	0006396	biological_process	RNA processing
Z	0008047	molecular_function	enzyme activator activity
Z	0030490	biological_process	maturation of SSU-rRNA
Z	0030686	cellular_component	90S preribosome
Z	0042254	biological_process	ribosome biogenesis
Z	0042274	biological_process	ribosomal small subunit biogenesis
Z	2000232	biological_process	regulation of rRNA processing
a	0000166	molecular_function	nucleotide binding
a	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0003723	molecular_function	RNA binding
a	0003729	molecular_function	mRNA binding
a	0003924	molecular_function	GTPase activity
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005525	molecular_function	GTP binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005739	cellular_component	mitochondrion
a	0016787	molecular_function	hydrolase activity
a	0016887	molecular_function	ATP hydrolysis activity
a	0030490	biological_process	maturation of SSU-rRNA
a	0030686	cellular_component	90S preribosome
a	0032040	cellular_component	small-subunit processome
a	0034511	molecular_function	U3 snoRNA binding
a	0042254	biological_process	ribosome biogenesis
a	0042274	biological_process	ribosomal small subunit biogenesis
a	2000232	biological_process	regulation of rRNA processing
b	0003723	molecular_function	RNA binding
b	0005730	cellular_component	nucleolus
b	0006364	biological_process	rRNA processing
b	0019843	molecular_function	rRNA binding
b	0030515	molecular_function	snoRNA binding
b	0032040	cellular_component	small-subunit processome
b	0034457	cellular_component	Mpp10 complex
b	0042254	biological_process	ribosome biogenesis
b	0042274	biological_process	ribosomal small subunit biogenesis
b	1990904	cellular_component	ribonucleoprotein complex
c	0005654	cellular_component	nucleoplasm
c	0005730	cellular_component	nucleolus
c	0006364	biological_process	rRNA processing
c	0019843	molecular_function	rRNA binding
c	0030515	molecular_function	snoRNA binding
c	0032040	cellular_component	small-subunit processome
c	0034457	cellular_component	Mpp10 complex
c	0042134	molecular_function	rRNA primary transcript binding
c	0042274	biological_process	ribosomal small subunit biogenesis
c	1990904	cellular_component	ribonucleoprotein complex
d	0004540	molecular_function	RNA nuclease activity
d	0005730	cellular_component	nucleolus
d	0006364	biological_process	rRNA processing
d	0032040	cellular_component	small-subunit processome
d	0042254	biological_process	ribosome biogenesis
d	0046872	molecular_function	metal ion binding
e	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
e	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
e	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005730	cellular_component	nucleolus
e	0005737	cellular_component	cytoplasm
e	0005880	cellular_component	nuclear microtubule
e	0006364	biological_process	rRNA processing
e	0008168	molecular_function	methyltransferase activity
e	0016740	molecular_function	transferase activity
e	0019843	molecular_function	rRNA binding
e	0030490	biological_process	maturation of SSU-rRNA
e	0030686	cellular_component	90S preribosome
e	0031167	biological_process	rRNA methylation
e	0032040	cellular_component	small-subunit processome
e	0032259	biological_process	methylation
e	0034399	cellular_component	nuclear periphery
e	0042254	biological_process	ribosome biogenesis
e	0042274	biological_process	ribosomal small subunit biogenesis
e	0042802	molecular_function	identical protein binding
e	0070037	molecular_function	rRNA (pseudouridine) methyltransferase activity
e	0070475	biological_process	rRNA base methylation
e	1990904	cellular_component	ribonucleoprotein complex
f	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
f	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
f	0000480	biological_process	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005730	cellular_component	nucleolus
f	0005737	cellular_component	cytoplasm
f	0005880	cellular_component	nuclear microtubule
f	0006364	biological_process	rRNA processing
f	0008168	molecular_function	methyltransferase activity
f	0016740	molecular_function	transferase activity
f	0019843	molecular_function	rRNA binding
f	0030490	biological_process	maturation of SSU-rRNA
f	0030686	cellular_component	90S preribosome
f	0031167	biological_process	rRNA methylation
f	0032040	cellular_component	small-subunit processome
f	0032259	biological_process	methylation
f	0034399	cellular_component	nuclear periphery
f	0042254	biological_process	ribosome biogenesis
f	0042274	biological_process	ribosomal small subunit biogenesis
f	0042802	molecular_function	identical protein binding
f	0070037	molecular_function	rRNA (pseudouridine) methyltransferase activity
f	0070475	biological_process	rRNA base methylation
f	1990904	cellular_component	ribonucleoprotein complex
g	0003676	molecular_function	nucleic acid binding
g	0003723	molecular_function	RNA binding
g	0005730	cellular_component	nucleolus
g	0006364	biological_process	rRNA processing
g	0032040	cellular_component	small-subunit processome
g	0042254	biological_process	ribosome biogenesis
g	1990904	cellular_component	ribonucleoprotein complex
h	0003676	molecular_function	nucleic acid binding
h	0003723	molecular_function	RNA binding
h	0005730	cellular_component	nucleolus
h	0006364	biological_process	rRNA processing
h	0032040	cellular_component	small-subunit processome
h	0042254	biological_process	ribosome biogenesis
h	1990904	cellular_component	ribonucleoprotein complex
i	0000049	molecular_function	tRNA binding
i	0000154	biological_process	rRNA modification
i	0000166	molecular_function	nucleotide binding
i	0005524	molecular_function	ATP binding
i	0005730	cellular_component	nucleolus
i	0006364	biological_process	rRNA processing
i	0008033	biological_process	tRNA processing
i	0008080	molecular_function	N-acetyltransferase activity
i	0009451	biological_process	RNA modification
i	0016072	biological_process	rRNA metabolic process
i	0016740	molecular_function	transferase activity
i	0016746	molecular_function	acyltransferase activity
i	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
i	0030686	cellular_component	90S preribosome
i	0042274	biological_process	ribosomal small subunit biogenesis
i	0046872	molecular_function	metal ion binding
i	0051391	biological_process	tRNA acetylation
i	0051392	molecular_function	tRNA cytidine N4-acetyltransferase activity
i	1904812	biological_process	rRNA acetylation involved in maturation of SSU-rRNA
i	1990883	molecular_function	18S rRNA cytidine N-acetyltransferase activity
j	0000049	molecular_function	tRNA binding
j	0000154	biological_process	rRNA modification
j	0000166	molecular_function	nucleotide binding
j	0005524	molecular_function	ATP binding
j	0005730	cellular_component	nucleolus
j	0006364	biological_process	rRNA processing
j	0008033	biological_process	tRNA processing
j	0008080	molecular_function	N-acetyltransferase activity
j	0009451	biological_process	RNA modification
j	0016072	biological_process	rRNA metabolic process
j	0016740	molecular_function	transferase activity
j	0016746	molecular_function	acyltransferase activity
j	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
j	0030686	cellular_component	90S preribosome
j	0042274	biological_process	ribosomal small subunit biogenesis
j	0046872	molecular_function	metal ion binding
j	0051391	biological_process	tRNA acetylation
j	0051392	molecular_function	tRNA cytidine N4-acetyltransferase activity
j	1904812	biological_process	rRNA acetylation involved in maturation of SSU-rRNA
j	1990883	molecular_function	18S rRNA cytidine N-acetyltransferase activity
o	0003735	molecular_function	structural constituent of ribosome
o	0005737	cellular_component	cytoplasm
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0022627	cellular_component	cytosolic small ribosomal subunit
o	1990904	cellular_component	ribonucleoprotein complex
p	0003723	molecular_function	RNA binding
p	0003735	molecular_function	structural constituent of ribosome
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0019843	molecular_function	rRNA binding
p	0022627	cellular_component	cytosolic small ribosomal subunit
p	1990904	cellular_component	ribonucleoprotein complex
q	0000054	biological_process	ribosomal subunit export from nucleus
q	0002181	biological_process	cytoplasmic translation
q	0003723	molecular_function	RNA binding
q	0003729	molecular_function	mRNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005515	molecular_function	protein binding
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0006450	biological_process	regulation of translational fidelity
q	0015935	cellular_component	small ribosomal subunit
q	0019843	molecular_function	rRNA binding
q	0022627	cellular_component	cytosolic small ribosomal subunit
q	0030490	biological_process	maturation of SSU-rRNA
q	0030686	cellular_component	90S preribosome
q	1990904	cellular_component	ribonucleoprotein complex
r	0003735	molecular_function	structural constituent of ribosome
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	1990904	cellular_component	ribonucleoprotein complex
s	0003735	molecular_function	structural constituent of ribosome
s	0005840	cellular_component	ribosome
s	0006364	biological_process	rRNA processing
s	0006412	biological_process	translation
s	0022627	cellular_component	cytosolic small ribosomal subunit
s	0030686	cellular_component	90S preribosome
s	0032040	cellular_component	small-subunit processome
s	0042274	biological_process	ribosomal small subunit biogenesis
s	1990904	cellular_component	ribonucleoprotein complex
t	0003735	molecular_function	structural constituent of ribosome
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	1990904	cellular_component	ribonucleoprotein complex
u	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
u	0003723	molecular_function	RNA binding
u	0003735	molecular_function	structural constituent of ribosome
u	0005515	molecular_function	protein binding
u	0005654	cellular_component	nucleoplasm
u	0005730	cellular_component	nucleolus
u	0005737	cellular_component	cytoplasm
u	0005829	cellular_component	cytosol
u	0005840	cellular_component	ribosome
u	0006364	biological_process	rRNA processing
u	0006412	biological_process	translation
u	0015935	cellular_component	small ribosomal subunit
u	0019843	molecular_function	rRNA binding
u	0022627	cellular_component	cytosolic small ribosomal subunit
u	0030476	biological_process	ascospore wall assembly
u	0030686	cellular_component	90S preribosome
u	0032040	cellular_component	small-subunit processome
u	0042254	biological_process	ribosome biogenesis
u	0042274	biological_process	ribosomal small subunit biogenesis
u	1990904	cellular_component	ribonucleoprotein complex
v	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
v	0002181	biological_process	cytoplasmic translation
v	0003735	molecular_function	structural constituent of ribosome
v	0005730	cellular_component	nucleolus
v	0005737	cellular_component	cytoplasm
v	0005829	cellular_component	cytosol
v	0005840	cellular_component	ribosome
v	0006412	biological_process	translation
v	0022627	cellular_component	cytosolic small ribosomal subunit
v	0030686	cellular_component	90S preribosome
v	0070181	molecular_function	small ribosomal subunit rRNA binding
v	1990904	cellular_component	ribonucleoprotein complex
w	0000028	biological_process	ribosomal small subunit assembly
w	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
w	0002181	biological_process	cytoplasmic translation
w	0003729	molecular_function	mRNA binding
w	0003735	molecular_function	structural constituent of ribosome
w	0005654	cellular_component	nucleoplasm
w	0005730	cellular_component	nucleolus
w	0005737	cellular_component	cytoplasm
w	0005829	cellular_component	cytosol
w	0005840	cellular_component	ribosome
w	0006364	biological_process	rRNA processing
w	0006412	biological_process	translation
w	0022627	cellular_component	cytosolic small ribosomal subunit
w	0030686	cellular_component	90S preribosome
w	0032040	cellular_component	small-subunit processome
w	0042254	biological_process	ribosome biogenesis
w	1990904	cellular_component	ribonucleoprotein complex
x	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
x	0003723	molecular_function	RNA binding
x	0003735	molecular_function	structural constituent of ribosome
x	0005737	cellular_component	cytoplasm
x	0005829	cellular_component	cytosol
x	0005840	cellular_component	ribosome
x	0006412	biological_process	translation
x	0006413	biological_process	translational initiation
x	0022627	cellular_component	cytosolic small ribosomal subunit
x	0030686	cellular_component	90S preribosome
x	1990904	cellular_component	ribonucleoprotein complex
y	0003735	molecular_function	structural constituent of ribosome
y	0005840	cellular_component	ribosome
y	0006412	biological_process	translation
y	0022627	cellular_component	cytosolic small ribosomal subunit
y	1990904	cellular_component	ribonucleoprotein complex
z	0002181	biological_process	cytoplasmic translation
z	0003735	molecular_function	structural constituent of ribosome
z	0005737	cellular_component	cytoplasm
z	0005829	cellular_component	cytosol
z	0005840	cellular_component	ribosome
z	0006412	biological_process	translation
z	0022627	cellular_component	cytosolic small ribosomal subunit
z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIIkhT

Chain	Residue	Details
q	GLU91-THR117

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR

Chain	Residue	Details
z	GLY100-ARG117

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD

Chain	Residue	Details
w	LEU102-ASP124

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiLvAgQcRPIS

Chain	Residue	Details
y	GLY119-SER131

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL

Chain	Residue	Details
x	GLY71-LEU89

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
v	VAL98-TYR128

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRINaPksWmLnK

Chain	Residue	Details
p	HIS8-LYS22

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. YGggKStGFAlVYDNqqyllkyE

Chain	Residue	Details
0	TYR62-GLU84

---

site_id	PS00566
Number of Residues	15
Details	FIBRILLARIN Fibrillarin signature. GKAYGVEFSpRvvRE

Chain	Residue	Details
W	GLY102-GLU116

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. IAGGnDkdGfPM

Chain	Residue	Details
r	ILE52-MET63

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI

Chain	Residue	Details
u	LEU105-ILE129

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IVSAslDsTIRTWDL

Chain	Residue	Details
I	ILE600-LEU614

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
1	GLU58-LEU66

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CdekkIPYvyVsSKkaLG

Chain	Residue	Details
U	CYS73-GLY90

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. IkGRVvEsTLaDL

Chain	Residue	Details
o	ILE63-LEU75

---

site_id	PS01287
Number of Residues	11
Details	RTC RNA 3'-terminal phosphate cyclase signature. RGspPlGGGeV

Chain	Residue	Details
Z	ARG156-VAL166

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	31
Details	Repeat: {"description":"WD 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	30
Details	Repeat: {"description":"WD 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	39
Details	Repeat: {"description":"WD 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	33
Details	Repeat: {"description":"WD 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	37
Details	Repeat: {"description":"WD 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	35
Details	Repeat: {"description":"WD 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	34
Details	Repeat: {"description":"WD 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	39
Details	Repeat: {"description":"WD 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	34
Details	Repeat: {"description":"WD 10","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	36
Details	Repeat: {"description":"WD 11","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	35
Details	Repeat: {"description":"WD 12","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	41
Details	Repeat: {"description":"WD 13","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24466140","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	12
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	39
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	39
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	39
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	38
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	38
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18063569","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	8
Details	Site: {"description":"Interaction with substrate rRNA","evidences":[{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	Site: {"description":"Stabilizes Arg-88","evidences":[{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	64
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"7890730","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"7890730","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	10
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P05755","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P05755","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1544921","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	20
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---