5JLW

AntpHD with 15bp DNA duplex R-monothioated at Cytidine-8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
D	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
D	0003677	molecular_function	DNA binding
D	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue NI A 101

Chain	Residue
A	HIS21
A	HOH206
D	HIS21
D	ASN60
D	HOH114

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site_id	AC2
Number of Residues	2
Details	binding site for residue NI B 101

Chain	Residue
B	DG1
C	HOH122

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site_id	AC3
Number of Residues	2
Details	binding site for residue NI B 102

Chain	Residue
B	DG12
B	HOH207

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site_id	AC4
Number of Residues	3
Details	binding site for residue NI B 103

Chain	Residue
B	DA3
B	DA4
C	DT13

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site_id	AC5
Number of Residues	3
Details	binding site for residue NI E 101

Chain	Residue
E	DG2
E	HOH205
E	HOH218

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site_id	AC6
Number of Residues	1
Details	binding site for residue NI E 102

Chain	Residue
E	DG13

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site_id	AC7
Number of Residues	2
Details	binding site for residue MPD F 101

Chain	Residue
F	DT13
F	MPD102

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site_id	AC8
Number of Residues	3
Details	binding site for residue MPD F 102

Chain	Residue
F	DT13
F	MPD101
F	MPD103

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site_id	AC9
Number of Residues	2
Details	binding site for residue MPD F 103

Chain	Residue
F	DT14
F	MPD102

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site_id	AD1
Number of Residues	8
Details	binding site for Di-nucleotide DC E 7 and C7R E 8

Chain	Residue
D	TYR25
D	GLN50
D	ARG53
D	MET54
E	DG6
E	DA9
F	DG9
F	DG10

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site_id	AD2
Number of Residues	7
Details	binding site for Di-nucleotide C7R E 8 and DA E 9

Chain	Residue
D	MET54
E	DC7
E	DT10
F	DA7
F	DT8
F	DG9
F	DG10

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Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. IAhaLsLTerQIKIWFqNrrmkwK

Chain	Residue	Details
A	ILE34-LYS57

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