Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005575 | cellular_component | cellular_component |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0020037 | molecular_function | heme binding |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005575 | cellular_component | cellular_component |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0020037 | molecular_function | heme binding |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070301 | biological_process | cellular response to hydrogen peroxide |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | GLY133 |
| A | LYS318 |
| A | THR319 |
| A | HIS320 |
| A | THR358 |
| A | SER359 |
| A | TRP365 |
| A | SER423 |
| A | HOH957 |
| A | HOH1058 |
| A | HOH1128 |
| A | LEU134 |
| A | HOH1462 |
| A | TRP140 |
| A | VAL274 |
| A | LEU309 |
| A | GLY313 |
| A | HIS314 |
| A | PHE316 |
| A | GLY317 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue FLC A 802 |
| Chain | Residue |
| A | ASP512 |
| A | VAL513 |
| A | SER514 |
| A | LYS596 |
| A | ASP600 |
| A | LYS692 |
| A | GLY693 |
| A | HOH975 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue FLC A 803 |
| Chain | Residue |
| A | ASP170 |
| A | VAL239 |
| A | PRO240 |
| A | LEU271 |
| A | ASN275 |
| A | PRO276 |
| A | GLU277 |
| A | SER359 |
| A | HOH1386 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | binding site for residue HEM B 1500 |
| Chain | Residue |
| B | GLY133 |
| B | LEU134 |
| B | TRP140 |
| B | VAL274 |
| B | LEU309 |
| B | ILE310 |
| B | GLY313 |
| B | HIS314 |
| B | PHE316 |
| B | GLY317 |
| B | LYS318 |
| B | THR319 |
| B | HIS320 |
| B | THR358 |
| B | SER359 |
| B | TRP365 |
| B | SER423 |
| B | HOH1640 |
| B | HOH1722 |
| B | HOH1736 |
| B | HOH1995 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue FLC B 1501 |
| Chain | Residue |
| B | ASP512 |
| B | VAL513 |
| B | SER514 |
| B | LYS692 |
| B | GLY693 |
| B | HOH2167 |
| B | HOH2236 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue FLC B 1502 |
| Chain | Residue |
| B | ASP170 |
| B | VAL239 |
| B | PRO240 |
| B | LEU271 |
| B | ASN275 |
| B | PRO276 |
| B | GLU277 |
| B | SER359 |
| B | HOH2155 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue FLC B 1503 |
| Chain | Residue |
| A | ARG439 |
| A | HIS443 |
| B | THR366 |
| B | LYS367 |
| B | GLY375 |
| B | HOH1612 |
| B | HOH1626 |
| B | HOH1657 |
| B | HOH2164 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide TRP B 140 and TYR B 273 |
| Chain | Residue |
| B | HEM1500 |
| B | HOH1732 |
| B | HOH1878 |
| B | HOH1995 |
| B | VAL136 |
| B | ARG137 |
| B | MET138 |
| B | ALA139 |
| B | HIS141 |
| B | SER142 |
| B | ALA143 |
| B | GLY144 |
| B | ALA266 |
| B | THR267 |
| B | LEU271 |
| B | ILE272 |
| B | VAL274 |
| B | PHE296 |
| B | MET299 |
| B | LEU458 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide TYR B 273 and MET B 299 |
| Chain | Residue |
| B | TRP140 |
| B | GLY144 |
| B | TYR146 |
| B | ALA265 |
| B | ALA266 |
| B | THR267 |
| B | LEU271 |
| B | ILE272 |
| B | VAL274 |
| B | ALA295 |
| B | PHE296 |
| B | GLY297 |
| B | ARG298 |
| B | GLY300 |
| B | MET301 |
| B | HOH1732 |
| B | HOH1878 |
| B | HOH1945 |
Functional Information from PROSITE/UniProt
| site_id | PS00435 |
| Number of Residues | 11 |
| Details | PEROXIDASE_1 Peroxidases proximal heme-ligand signature. TVALIAGGHAF |
| Chain | Residue | Details |
| A | THR306-PHE316 | |
| site_id | PS00436 |
| Number of Residues | 12 |
| Details | PEROXIDASE_2 Peroxidases active site signature. GGlfVRMaWHSA |
| Chain | Residue | Details |
| A | GLY132-ALA143 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | HIS141 | |
| B | HIS141 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | HIS314 | |
| B | HIS314 | |
| Chain | Residue | Details |
| A | ARG137 | |
| B | ARG137 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN248 | |
| B | ASN572 | |
| A | ASN302 | |
| A | ASN384 | |
| A | ASN401 | |
| A | ASN572 | |
| B | ASN248 | |
| B | ASN302 | |
| B | ASN384 | |
| B | ASN401 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CROSSLNK: Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-299) |
| Chain | Residue | Details |
| A | TRP140 | |
| B | TRP140 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CROSSLNK: Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-140) |
| Chain | Residue | Details |
| A | TYR273 | |
| A | MET299 | |
| B | TYR273 | |
| B | MET299 | |
