Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004032 | molecular_function | aldose reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue A2P A 401 |
| Chain | Residue |
| A | HIS84 |
| A | THR254 |
| A | ARG258 |
| A | ASN262 |
| A | EDO402 |
| A | HOH510 |
| A | HOH523 |
| A | HOH657 |
| A | SER203 |
| A | PRO204 |
| A | LEU205 |
| A | GLY206 |
| A | LEU218 |
| A | ALA235 |
| A | LYS252 |
| A | SER253 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | TRP21 |
| A | A2P401 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | ARG47 |
| A | TRP80 |
| A | ARG258 |
| A | HOH593 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. MeklydagkARAIGVSNF |
| Chain | Residue | Details |
| A | MET139-PHE156 | |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. LPKSTNeeRIkQNlDV |
| Chain | Residue | Details |
| A | LEU250-VAL265 | |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRHIDCArvygnEkeIG |
| Chain | Residue | Details |
| A | GLY39-GLY56 | |
