Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0016491 | molecular_function | oxidoreductase activity |
B | 0000166 | molecular_function | nucleotide binding |
B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 33 |
Details | binding site for residue 6KB A 401 |
Chain | Residue |
A | GLY29 |
A | TYR213 |
A | SER214 |
A | PRO215 |
A | LEU216 |
A | GLY217 |
A | SER218 |
A | SER219 |
A | ASN222 |
A | ILE256 |
A | PRO257 |
A | THR30 |
A | LYS258 |
A | SER259 |
A | THR260 |
A | ARG261 |
A | ARG264 |
A | ASN268 |
A | LEU294 |
A | EDO402 |
A | HOH547 |
A | HOH555 |
A | TRP31 |
A | HOH568 |
A | HOH624 |
A | HOH685 |
A | HOH721 |
A | ASP54 |
A | TYR59 |
A | LYS87 |
A | HIS120 |
A | ASN166 |
A | GLN187 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue EDO A 402 |
Chain | Residue |
A | TRP31 |
A | GLN58 |
A | TYR59 |
A | HIS120 |
A | 6KB401 |
A | HOH523 |
A | HOH547 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue EDO A 403 |
Chain | Residue |
A | GLY34 |
A | SER35 |
A | GLY60 |
A | HOH674 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue EDO A 404 |
Chain | Residue |
A | GLN58 |
A | LEU294 |
A | GLU298 |
A | LEU299 |
A | HOH523 |
A | HOH530 |
A | HOH562 |
site_id | AC5 |
Number of Residues | 2 |
Details | binding site for residue EDO A 405 |
Chain | Residue |
A | GLU220 |
A | HOH538 |
site_id | AC6 |
Number of Residues | 34 |
Details | binding site for residue 6KB B 401 |
Chain | Residue |
A | ASP112 |
B | GLY29 |
B | THR30 |
B | TRP31 |
B | ASP54 |
B | TYR59 |
B | LYS87 |
B | HIS120 |
B | ASN166 |
B | GLN187 |
B | TYR213 |
B | SER214 |
B | PRO215 |
B | LEU216 |
B | GLY217 |
B | SER218 |
B | SER219 |
B | ASN222 |
B | ILE256 |
B | PRO257 |
B | LYS258 |
B | SER259 |
B | THR260 |
B | ARG261 |
B | ARG264 |
B | ASN268 |
B | LEU294 |
B | EDO404 |
B | HOH531 |
B | HOH539 |
B | HOH563 |
B | HOH671 |
B | HOH684 |
B | HOH720 |
site_id | AC7 |
Number of Residues | 5 |
Details | binding site for residue EDO B 402 |
Chain | Residue |
B | ASP161 |
B | ILE162 |
B | PRO182 |
B | HOH527 |
B | HOH659 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue EDO B 403 |
Chain | Residue |
A | ARG99 |
B | GLY34 |
B | SER35 |
B | GLY60 |
B | EDO405 |
B | HOH507 |
B | HOH658 |
site_id | AC9 |
Number of Residues | 8 |
Details | binding site for residue EDO B 404 |
Chain | Residue |
B | TRP31 |
B | GLN58 |
B | TYR59 |
B | HIS120 |
B | LEU294 |
B | 6KB401 |
B | HOH509 |
B | HOH531 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue EDO B 405 |
Chain | Residue |
A | ARG99 |
A | GLU103 |
B | SER35 |
B | EDO403 |
B | HOH611 |
site_id | AD2 |
Number of Residues | 2 |
Details | binding site for residue EDO B 406 |
Chain | Residue |
B | ARG99 |
B | GLU103 |
site_id | AD3 |
Number of Residues | 8 |
Details | binding site for residue EDO B 407 |
Chain | Residue |
B | PHE123 |
B | ARG124 |
B | LEU139 |
B | GLU140 |
B | LEU141 |
B | TYR308 |
B | HOH585 |
B | HOH653 |
site_id | AD4 |
Number of Residues | 8 |
Details | binding site for residue EDO B 408 |
Chain | Residue |
B | GLN58 |
B | LEU294 |
B | GLU298 |
B | LEU299 |
B | HOH509 |
B | HOH516 |
B | HOH530 |
B | HOH724 |
Functional Information from PROSITE/UniProt
site_id | PS00062 |
Number of Residues | 18 |
Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. MeglvkdglVKDIGVCNY |
Chain | Residue | Details |
A | MET150-TYR167 | |
site_id | PS00798 |
Number of Residues | 18 |
Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRHVDTAaqygvEkeVG |
Chain | Residue | Details |
A | GLY49-GLY66 | |