Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MPD A 301 |
| Chain | Residue |
| A | MET227 |
| A | LYS230 |
| A | TYR231 |
| A | ARG243 |
| A | HOH439 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MRD A 302 |
| Chain | Residue |
| A | LYS140 |
| A | THR143 |
| A | TYR202 |
| B | VAL205 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide ACE C 1 and ASP C 2 |
| Chain | Residue |
| B | ARG212 |
| B | ASN213 |
| B | THR214 |
| B | GLU253 |
| B | SER254 |
| B | THR255 |
| C | GLU3 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide ASP C 5 and 0QE C 6 |
| Chain | Residue |
| B | ARG67 |
| B | SER123 |
| B | HIS124 |
| B | GLY125 |
| B | GLN164 |
| B | ALA165 |
| B | CYS166 |
| B | SER210 |
| B | ARG212 |
| C | VAL4 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide ACE F 1 and ASP F 2 |
| Chain | Residue |
| A | ARG212 |
| A | ASN213 |
| A | THR214 |
| A | SER254 |
| A | THR255 |
| F | GLU3 |
| F | HOH101 |
| F | HOH102 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide ASP F 5 and 0QE F 6 |
| Chain | Residue |
| A | ARG67 |
| A | HIS124 |
| A | GLY125 |
| A | GLN164 |
| A | CYS166 |
| A | SER210 |
| A | ARG212 |
| F | VAL4 |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HsrcaSlvCvLLSHG |
| Chain | Residue | Details |
| A | HIS111-GLY125 | |
| site_id | PS01122 |
| Number of Residues | 12 |
| Details | CASPASE_CYS Caspase family cysteine active site. KPKLFFIQACRG |
| Chain | Residue | Details |
| A | LYS157-GLY168 | |
5JFT
