5JCK

Structure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003729	molecular_function	mRNA binding
A	0005737	cellular_component	cytoplasm
A	0005782	cellular_component	peroxisomal matrix
A	0016491	molecular_function	oxidoreductase activity
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0016656	molecular_function	monodehydroascorbate reductase (NADH) activity
A	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	36
Details	binding site for residue FAD A 500

Chain	Residue
A	GLY13
A	PRO49
A	SER52
A	LYS53
A	THR94
A	GLU95
A	ILE96
A	ALA122
A	THR123
A	GLY124
A	ARG147
A	GLY14
A	GLU148
A	LEU265
A	GLY297
A	ASP298
A	GLU314
A	HIS315
A	VAL316
A	ALA319
A	TYR349
A	NAD501
A	GLY15
A	HOH621
A	HOH686
A	HOH708
A	HOH712
A	HOH726
A	HOH730
A	HOH826
A	VAL16
A	ALA17
A	SER39
A	LYS40
A	GLU41
A	ARG48

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site_id	AC2
Number of Residues	30
Details	binding site for residue NAD A 501

Chain	Residue
A	PHE133
A	VAL170
A	GLY171
A	GLY172
A	GLY173
A	TYR174
A	ILE175
A	GLU178
A	PHE194
A	PRO195
A	GLU196
A	PRO201
A	ARG202
A	GLY259
A	VAL260
A	GLY261
A	GLU314
A	HIS315
A	TYR349
A	FAD500
A	HOH617
A	HOH665
A	HOH691
A	HOH727
A	HOH730
A	HOH731
A	HOH732
A	HOH788
A	HOH847
A	HOH878

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:27652777, ECO:0007744|PDB:5JCI

Chain	Residue	Details
A	GLY14
A	GLU41
A	ARG48
A	LYS53
A	ILE96
A	ARG147
A	ASP298
A	VAL316

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:27652777, ECO:0007744|PDB:5JCK

Chain	Residue	Details
A	GLY172
A	GLU196

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site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:27652777, ECO:0007744|PDB:5JCL

Chain	Residue	Details
A	TYR174
A	ARG202
A	GLY261
A	GLU314
A	TYR349

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:27652777, ECO:0007744|PDB:5JCN

Chain	Residue	Details
A	ARG320
A	ARG351

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