5JC6

Carboxypeptidase B with 2-nd zinc and acetate ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004181	molecular_function	metallocarboxypeptidase activity
A	0006508	biological_process	proteolysis
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue ZN A 401

Chain	Residue
A	HIS69
A	GLU72
A	HIS196
A	ZN402
A	ACT406
A	HOH549

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 402

Chain	Residue
A	HOH549
A	GLU270
A	ZN401
A	ACT406

---

site_id	AC3
Number of Residues	5
Details	binding site for residue ZN A 403

Chain	Residue
A	GLU85
A	ASP159
A	ASP162
A	GLU291
A	HOH526

---

site_id	AC4
Number of Residues	3
Details	binding site for residue ZN A 404

Chain	Residue
A	GLU19
A	HOH628
A	HOH630

---

site_id	AC5
Number of Residues	1
Details	binding site for residue ZN A 405

Chain	Residue
A	HIS7

---

site_id	AC6
Number of Residues	8
Details	binding site for residue ACT A 406

Chain	Residue
A	HIS69
A	ASN144
A	ARG145
A	GLU270
A	ZN401
A	ZN402
A	HOH513
A	HOH549

---

Functional Information from PROSITE/UniProt

site_id	PS00132
Number of Residues	23
Details	CARBOXYPEPT_ZN_1 Zinc carboxypeptidases, zinc-binding region 1 signature. PaIfMdcGfHArEwISHafcqwF

Chain	Residue	Details
A	PRO60-PHE82

---

site_id	PS00133
Number of Residues	11
Details	CARBOXYPEPT_ZN_2 Zinc carboxypeptidases, zinc-binding region 2 signature. HSYSQMIlYPY

Chain	Residue	Details
A	HIS196-TYR206

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	294
Details	Domain: {"description":"Peptidase M14","evidences":[{"source":"PROSITE-ProRule","id":"PRU01379","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01379","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00730","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01379","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---