5JAB
Structure of the biliverdin reductase Rv2074 from Mycobacterium tuberculosis in complex with F420
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0009986 | cellular_component | cell surface |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
| A | 0070967 | molecular_function | coenzyme F420 binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0009986 | cellular_component | cell surface |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0055114 | biological_process | obsolete oxidation-reduction process |
| B | 0070967 | molecular_function | coenzyme F420 binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C | 0009986 | cellular_component | cell surface |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0055114 | biological_process | obsolete oxidation-reduction process |
| C | 0070967 | molecular_function | coenzyme F420 binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0009274 | cellular_component | peptidoglycan-based cell wall |
| D | 0009986 | cellular_component | cell surface |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0055114 | biological_process | obsolete oxidation-reduction process |
| D | 0070967 | molecular_function | coenzyme F420 binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue 6J4 A 201 |
| Chain | Residue |
| A | HIS36 |
| A | LYS61 |
| A | ARG67 |
| A | HOH327 |
| A | HOH330 |
| A | HOH332 |
| A | HOH342 |
| A | HOH351 |
| A | HOH358 |
| A | HOH368 |
| A | HOH391 |
| A | VAL38 |
| A | HOH406 |
| A | HOH408 |
| A | HOH415 |
| A | HOH417 |
| B | ARG9 |
| B | GLY78 |
| B | ALA79 |
| B | TRP81 |
| B | ARG126 |
| A | ALA39 |
| A | VAL40 |
| A | GLY41 |
| A | ILE54 |
| A | THR55 |
| A | GLY58 |
| A | GLN60 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 202 |
| Chain | Residue |
| A | THR55 |
| A | ASN114 |
| A | ARG117 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | binding site for residue 6J4 B 201 |
| Chain | Residue |
| A | MET1 |
| A | GLY78 |
| A | ALA79 |
| A | TRP81 |
| B | HIS36 |
| B | VAL38 |
| B | ALA39 |
| B | VAL40 |
| B | GLY41 |
| B | ILE54 |
| B | THR55 |
| B | GLY58 |
| B | GLN60 |
| B | LYS61 |
| B | ARG67 |
| B | HOH306 |
| B | HOH310 |
| B | HOH317 |
| B | HOH322 |
| B | HOH324 |
| B | HOH329 |
| B | HOH330 |
| B | HOH362 |
| B | HOH364 |
| B | HOH383 |
| B | HOH392 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 202 |
| Chain | Residue |
| B | THR55 |
| B | ASN114 |
| B | ARG117 |
| B | HOH352 |
| site_id | AC5 |
| Number of Residues | 29 |
| Details | binding site for residue 6J4 C 201 |
| Chain | Residue |
| C | HIS36 |
| C | VAL38 |
| C | ALA39 |
| C | VAL40 |
| C | GLY41 |
| C | ILE54 |
| C | THR55 |
| C | GLY58 |
| C | SER59 |
| C | GLN60 |
| C | LYS61 |
| C | ARG67 |
| C | HOH326 |
| C | HOH330 |
| C | HOH343 |
| C | HOH349 |
| C | HOH351 |
| C | HOH360 |
| C | HOH363 |
| C | HOH366 |
| C | HOH370 |
| C | HOH378 |
| C | HOH381 |
| C | HOH401 |
| D | GLY78 |
| D | ALA79 |
| D | TRP81 |
| D | ARG126 |
| D | LEU128 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 202 |
| Chain | Residue |
| C | THR55 |
| C | ASN114 |
| C | ARG117 |
| site_id | AC7 |
| Number of Residues | 29 |
| Details | binding site for residue 6J4 D 201 |
| Chain | Residue |
| D | VAL38 |
| D | ALA39 |
| D | VAL40 |
| D | GLY41 |
| D | ILE54 |
| D | THR55 |
| D | GLY58 |
| D | GLN60 |
| D | LYS61 |
| D | ARG67 |
| D | HOH305 |
| D | HOH313 |
| D | HOH319 |
| D | HOH320 |
| D | HOH322 |
| D | HOH328 |
| D | HOH330 |
| D | HOH354 |
| D | HOH365 |
| D | HOH366 |
| D | HOH370 |
| D | HOH379 |
| D | HOH388 |
| C | GLY78 |
| C | ALA79 |
| C | TRP81 |
| C | ARG126 |
| C | LEU128 |
| D | HIS36 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 202 |
| Chain | Residue |
| D | THR55 |
| D | ASN114 |
| D | ARG117 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: in other chain => ECO:0000269|PubMed:27364382 |
| Chain | Residue | Details |
| A | HIS36 | |
| C | ILE54 | |
| C | GLN60 | |
| C | ARG67 | |
| D | HIS36 | |
| D | ILE54 | |
| D | GLN60 | |
| D | ARG67 | |
| A | ILE54 | |
| A | GLN60 | |
| A | ARG67 | |
| B | HIS36 | |
| B | ILE54 | |
| B | GLN60 | |
| B | ARG67 | |
| C | HIS36 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27364382 |
| Chain | Residue | Details |
| A | GLY78 | |
| B | GLY78 | |
| C | GLY78 | |
| D | GLY78 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20066036 |
| Chain | Residue | Details |
| A | LYS47 | |
| B | LYS47 | |
| C | LYS47 | |
| D | LYS47 |
