5JA2
EntF, a Terminal Nonribosomal Peptide Synthetase Module Bound to the non-Native MbtH-Like Protein PA2412
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009239 | biological_process | enterobactin biosynthetic process |
| A | 0009366 | cellular_component | enterobactin synthetase complex |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0031177 | molecular_function | phosphopantetheine binding |
| A | 0043041 | biological_process | amino acid activation for nonribosomal peptide biosynthetic process |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0047527 | molecular_function | 2,3-dihydroxybenzoate-serine ligase activity |
| B | 0002049 | biological_process | pyoverdine biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0019290 | biological_process | siderophore biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue 75C A 1301 |
| Chain | Residue |
| A | PHE647 |
| A | LEU745 |
| A | TYR746 |
| A | GLY747 |
| A | THR749 |
| A | VAL753 |
| A | ASP754 |
| A | ASP840 |
| A | TYR852 |
| A | ARG855 |
| A | LYS861 |
| A | ASP648 |
| A | ARG863 |
| A | GLY864 |
| A | GLN865 |
| A | ARG866 |
| A | SER1006 |
| A | HOH1410 |
| A | ARG673 |
| A | VAL693 |
| A | SER722 |
| A | GLY723 |
| A | GLU724 |
| A | ALA725 |
| A | ASN744 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue BU9 A 1302 |
| Chain | Residue |
| A | SER606 |
| A | LYS611 |
| A | SER822 |
| A | ARG823 |
| A | ARG837 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue BU9 A 1303 |
| Chain | Residue |
| A | LEU109 |
| A | ARG110 |
| A | SER113 |
| A | LYS115 |
| A | PRO116 |
| A | ARG135 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 405 |
| Details | Region: {"description":"Adenylatione","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor; for thioesterase activity","evidences":[{"source":"PubMed","id":"10375542","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"source":"PubMed","id":"10375542","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26762461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27597544","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
