5JA1

EntF, a Terminal Nonribosomal Peptide Synthetase Module Bound to the MbtH-Like Protein YbdZ

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0009058	biological_process	biosynthetic process
A	0009239	biological_process	enterobactin biosynthetic process
A	0009366	cellular_component	enterobactin synthetase complex
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016874	molecular_function	ligase activity
A	0031177	molecular_function	phosphopantetheine binding
A	0043041	biological_process	amino acid activation for nonribosomal peptide biosynthetic process
A	0044550	biological_process	secondary metabolite biosynthetic process
A	0047527	molecular_function	2,3-dihydroxybenzoate-serine ligase activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0009239	biological_process	enterobactin biosynthetic process
B	0019290	biological_process	siderophore biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	27
Details	binding site for residue 75C A 1301

Chain	Residue
A	PHE647
A	LEU745
A	TYR746
A	GLY747
A	PRO748
A	THR749
A	VAL753
A	ASP754
A	ILE775
A	ASP840
A	TYR852
A	ASP648
A	ARG855
A	LYS861
A	ARG863
A	GLY864
A	GLN865
A	ARG866
A	SER1006
A	HOH1420
A	ARG673
A	VAL693
A	SER722
A	GLY723
A	GLU724
A	ALA725
A	ASN744

---

site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 1302

Chain	Residue
A	LYS861
A	ARG903

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Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. ALGGHSLLAMKLAAQL

Chain	Residue	Details
A	ALA1001-LEU1016

---

site_id	PS00455
Number of Residues	12
Details	AMP_BINDING Putative AMP-binding domain signature. IIFTSGSTGrPK

Chain	Residue	Details
A	ILE600-LYS611

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	405
Details	Region: {"description":"Adenylatione","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor; for thioesterase activity","evidences":[{"source":"PubMed","id":"10375542","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"source":"PubMed","id":"10375542","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26762461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27597544","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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