5J8Q

Crystal Structure of the Cysteine Desulfurase SufS of Bacillus subtilis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0006534	biological_process	cysteine metabolic process
A	0016740	molecular_function	transferase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031071	molecular_function	cysteine desulfurase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue PLP A 501

Chain	Residue
A	THR92
A	LYS224
A	THR275
A	ALA502
A	HOH660
A	HOH678
A	THR93
A	HIS121
A	ASN173
A	ASP198
A	ALA200
A	GLN201
A	SER221
A	HIS223

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site_id	AC2
Number of Residues	8
Details	binding site for residue ALA A 502

Chain	Residue
A	ALA28
A	ALA29
A	HIS121
A	ASN173
A	ARG356
A	HIS360
A	ARG376
A	PLP501

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Functional Information from PROSITE/UniProt

site_id	PS00595
Number of Residues	20
Details	AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. CDFFalSSHKmcgpt.GvGvL

Chain	Residue	Details
A	CYS215-LEU234

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Cysteine persulfide intermediate => ECO:0000269|PubMed:27382962, ECO:0000269|PubMed:31587510

Chain	Residue	Details
A	CSS361

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:31587510, ECO:0007744|PDB:5J8Q

Chain	Residue	Details
A	LYS224

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