5J8G
Structure of nitroreductase from E. cloacae complexed with para-nitrobenzoic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| A | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| B | 0005829 | cellular_component | cytosol |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| B | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| C | 0005829 | cellular_component | cytosol |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| C | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| D | 0005829 | cellular_component | cytosol |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| D | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue FMN A 301 |
| Chain | Residue |
| A | ARG10 |
| A | GLY166 |
| A | LYS205 |
| A | ARG207 |
| A | HOH424 |
| A | HOH451 |
| A | HOH502 |
| A | HOH508 |
| B | PRO38 |
| B | SER39 |
| B | SER40 |
| A | HIS11 |
| B | ASN42 |
| B | LEU145 |
| B | 4NB302 |
| A | SER12 |
| A | LYS14 |
| A | ASN71 |
| A | LYS74 |
| A | PRO163 |
| A | ILE164 |
| A | GLU165 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue 4NB A 302 |
| Chain | Residue |
| A | SER40 |
| A | THR41 |
| A | PHE124 |
| A | HOH402 |
| A | HOH491 |
| B | TYR68 |
| B | GLU165 |
| B | GLY166 |
| B | FMN301 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | binding site for residue FMN B 301 |
| Chain | Residue |
| A | PRO38 |
| A | SER39 |
| A | SER40 |
| A | ASN42 |
| A | LEU145 |
| A | 4NB302 |
| B | ARG10 |
| B | HIS11 |
| B | SER12 |
| B | LYS14 |
| B | ASN71 |
| B | LYS74 |
| B | PRO163 |
| B | ILE164 |
| B | GLU165 |
| B | GLY166 |
| B | LYS205 |
| B | ARG207 |
| B | HOH418 |
| B | HOH453 |
| B | HOH477 |
| B | HOH497 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue 4NB B 302 |
| Chain | Residue |
| A | TYR68 |
| A | GLU165 |
| A | GLY166 |
| A | FMN301 |
| A | HOH511 |
| B | SER40 |
| B | THR41 |
| B | PHE124 |
| B | HOH454 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | binding site for residue FMN C 301 |
| Chain | Residue |
| C | ARG10 |
| C | HIS11 |
| C | SER12 |
| C | LYS14 |
| C | ASN71 |
| C | LYS74 |
| C | PRO163 |
| C | ILE164 |
| C | GLU165 |
| C | GLY166 |
| C | LYS205 |
| C | ARG207 |
| C | HOH443 |
| C | HOH471 |
| C | HOH487 |
| C | HOH491 |
| D | PRO38 |
| D | SER39 |
| D | SER40 |
| D | ASN42 |
| D | LEU145 |
| D | 4NB302 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue 4NB C 302 |
| Chain | Residue |
| C | SER40 |
| C | THR41 |
| C | PHE124 |
| D | TYR68 |
| D | GLU165 |
| D | GLY166 |
| D | FMN301 |
| site_id | AC7 |
| Number of Residues | 22 |
| Details | binding site for residue FMN D 301 |
| Chain | Residue |
| D | SER12 |
| D | LYS14 |
| D | ASN71 |
| D | LYS74 |
| D | PRO163 |
| D | ILE164 |
| D | GLU165 |
| D | GLY166 |
| D | LYS205 |
| D | ARG207 |
| D | HOH429 |
| D | HOH447 |
| D | HOH476 |
| D | HOH504 |
| C | PRO38 |
| C | SER39 |
| C | SER40 |
| C | ASN42 |
| C | LEU145 |
| C | 4NB302 |
| D | ARG10 |
| D | HIS11 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue 4NB D 302 |
| Chain | Residue |
| C | TYR68 |
| C | GLU165 |
| C | GLY166 |
| C | FMN301 |
| D | SER40 |
| D | THR41 |
| D | PHE124 |
| D | HOH405 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28578873","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5J8D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28578873","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5J8D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
