5J5A

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 70786556)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004825	molecular_function	methionine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006431	biological_process	methionyl-tRNA aminoacylation
B	0000166	molecular_function	nucleotide binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004825	molecular_function	methionine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006431	biological_process	methionyl-tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue MET A 800

Chain	Residue
A	ILE248
A	LYS550
A	HOH910
A	TYR250
A	ASP287
A	TRP474
A	ALA477
A	LEU478
A	TYR481
A	ILE519
A	HIS523

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site_id	AC2
Number of Residues	11
Details	binding site for residue 756 B 801

Chain	Residue
B	ILE248
B	TYR250
B	ASP287
B	HIS289
B	GLY290
B	VAL473
B	ASP476
B	LEU478
B	TYR481
B	PHE522
B	HIS523

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