5J16

Crystal structure of Inositol monophosphate bound SaIMPase-II

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006020	biological_process	inositol metabolic process
A	0007165	biological_process	signal transduction
A	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
A	0016787	molecular_function	hydrolase activity
A	0016791	molecular_function	phosphatase activity
A	0046872	molecular_function	metal ion binding
B	0006020	biological_process	inositol metabolic process
B	0007165	biological_process	signal transduction
B	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
B	0016787	molecular_function	hydrolase activity
B	0016791	molecular_function	phosphatase activity
B	0046872	molecular_function	metal ion binding
C	0006020	biological_process	inositol metabolic process
C	0007165	biological_process	signal transduction
C	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
C	0016787	molecular_function	hydrolase activity
C	0016791	molecular_function	phosphatase activity
C	0046872	molecular_function	metal ion binding
D	0006020	biological_process	inositol metabolic process
D	0007165	biological_process	signal transduction
D	0008934	molecular_function	inositol monophosphate 1-phosphatase activity
D	0016787	molecular_function	hydrolase activity
D	0016791	molecular_function	phosphatase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 301

Chain	Residue
A	ASP83
A	ASP86
A	ASP208
A	IPD303
A	HOH437

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CA A 302

Chain	Residue
A	IPD303
A	ASP42
A	GLU65
A	ASP83
A	ILE85

---

site_id	AC3
Number of Residues	14
Details	binding site for residue IPD A 303

Chain	Residue
A	GLU65
A	ASP83
A	ILE85
A	ASP86
A	GLY87
A	THR88
A	GLY182
A	SER183
A	ALA184
A	ARG203
A	CA301
A	CA302
A	HOH421
A	HOH436

---

site_id	AC4
Number of Residues	5
Details	binding site for residue CA B 301

Chain	Residue
B	ASP83
B	ASP86
B	ASP208
B	IPD303
B	HOH434

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CA B 302

Chain	Residue
B	GLU65
B	ASP83
B	ILE85
B	IPD303
B	HOH425
B	HOH441

---

site_id	AC6
Number of Residues	14
Details	binding site for residue IPD B 303

Chain	Residue
B	GLU65
B	ASP83
B	ILE85
B	ASP86
B	GLY87
B	THR88
B	GLY182
B	SER183
B	ALA184
B	CA301
B	CA302
B	HOH403
B	HOH425
B	HOH433

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CA C 301

Chain	Residue
C	ASP83
C	ASP86
C	ASP208
C	IPD303
C	HOH429

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CA C 302

Chain	Residue
C	GLU65
C	ASP83
C	ILE85
C	IPD303
C	HOH403
C	HOH416

---

site_id	AC9
Number of Residues	15
Details	binding site for residue IPD C 303

Chain	Residue
C	GLU65
C	ASP83
C	ILE85
C	ASP86
C	GLY87
C	THR88
C	GLY182
C	SER183
C	ALA184
C	LEU204
C	CA301
C	CA302
C	HOH416
C	HOH428
C	HOH434

---

site_id	AD1
Number of Residues	5
Details	binding site for residue CA D 301

Chain	Residue
D	ASP83
D	ASP86
D	ASP208
D	PO4303
D	HOH403

---

site_id	AD2
Number of Residues	5
Details	binding site for residue CA D 302

Chain	Residue
D	GLU65
D	ASP83
D	ILE85
D	PO4303
D	HOH430

---

site_id	AD3
Number of Residues	9
Details	binding site for residue PO4 D 303

Chain	Residue
D	GLU65
D	ASP83
D	ILE85
D	ASP86
D	GLY87
D	THR88
D	CA301
D	CA302
D	HOH433

---

Functional Information from PROSITE/UniProt

site_id	PS00629
Number of Residues	14
Details	IMP_1 Inositol monophosphatase family signature 1. WvVDPIDGTlnFvH

Chain	Residue	Details
A	TRP80-HIS93

---