5IXV
Crystal structure of the signaling protein complex 2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004383 | molecular_function | guanylate cyclase activity |
| A | 0006182 | biological_process | cGMP biosynthetic process |
| A | 0008074 | cellular_component | guanylate cyclase complex, soluble |
| A | 0019934 | biological_process | cGMP-mediated signaling |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070482 | biological_process | response to oxygen levels |
| B | 0004383 | molecular_function | guanylate cyclase activity |
| B | 0006182 | biological_process | cGMP biosynthetic process |
| B | 0008074 | cellular_component | guanylate cyclase complex, soluble |
| B | 0019934 | biological_process | cGMP-mediated signaling |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070482 | biological_process | response to oxygen levels |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue HEM A 201 |
| Chain | Residue |
| A | MET1 |
| A | HIS105 |
| A | LEU115 |
| A | ARG116 |
| A | PRO118 |
| A | TYR134 |
| A | SER136 |
| A | ARG138 |
| A | MET144 |
| A | VAL145 |
| A | LEU148 |
| A | TYR2 |
| A | 1MZ202 |
| A | HOH305 |
| A | HOH353 |
| A | LEU4 |
| A | TRP74 |
| A | LEU87 |
| A | PHE97 |
| A | MET98 |
| A | LEU101 |
| A | LEU104 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue 1MZ A 202 |
| Chain | Residue |
| A | PHE70 |
| A | TRP74 |
| A | HEM201 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MLI A 203 |
| Chain | Residue |
| A | MET12 |
| A | HIS16 |
| A | HIS17 |
| A | LYS61 |
| A | LEU66 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | binding site for residue HEM B 501 |
| Chain | Residue |
| B | MET1 |
| B | TYR2 |
| B | LEU4 |
| B | TRP74 |
| B | LEU87 |
| B | PHE97 |
| B | LEU101 |
| B | LEU104 |
| B | HIS105 |
| B | LEU115 |
| B | ARG116 |
| B | PRO118 |
| B | TYR134 |
| B | SER136 |
| B | ARG138 |
| B | LEU141 |
| B | MET144 |
| B | VAL145 |
| B | LEU148 |
| B | 1MZ502 |
| B | HOH604 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue 1MZ B 502 |
| Chain | Residue |
| B | VAL5 |
| B | TRP74 |
| B | LEU148 |
| B | HEM501 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MLI B 503 |
| Chain | Residue |
| B | HIS16 |
| B | HIS17 |
| B | LYS61 |
| B | ALA69 |
