Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5IXL

Structure of P. vulgaris HigB toxin Y91A variant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004521	molecular_function	RNA endonuclease activity
A	0005515	molecular_function	protein binding
A	0006276	biological_process	plasmid maintenance
A	0006401	biological_process	RNA catabolic process
A	0008285	biological_process	negative regulation of cell population proliferation
A	0016787	molecular_function	hydrolase activity
A	0017148	biological_process	negative regulation of translation
A	0030308	biological_process	negative regulation of cell growth
A	0030371	molecular_function	translation repressor activity
A	0043022	molecular_function	ribosome binding
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0004521	molecular_function	RNA endonuclease activity
B	0005515	molecular_function	protein binding
B	0006276	biological_process	plasmid maintenance
B	0006401	biological_process	RNA catabolic process
B	0008285	biological_process	negative regulation of cell population proliferation
B	0016787	molecular_function	hydrolase activity
B	0017148	biological_process	negative regulation of translation
B	0030308	biological_process	negative regulation of cell growth
B	0030371	molecular_function	translation repressor activity
B	0043022	molecular_function	ribosome binding
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0004521	molecular_function	RNA endonuclease activity
C	0005515	molecular_function	protein binding
C	0006276	biological_process	plasmid maintenance
C	0006401	biological_process	RNA catabolic process
C	0008285	biological_process	negative regulation of cell population proliferation
C	0016787	molecular_function	hydrolase activity
C	0017148	biological_process	negative regulation of translation
C	0030308	biological_process	negative regulation of cell growth
C	0030371	molecular_function	translation repressor activity
C	0043022	molecular_function	ribosome binding
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004521	molecular_function	RNA endonuclease activity
D	0005515	molecular_function	protein binding
D	0006276	biological_process	plasmid maintenance
D	0006401	biological_process	RNA catabolic process
D	0008285	biological_process	negative regulation of cell population proliferation
D	0016787	molecular_function	hydrolase activity
D	0017148	biological_process	negative regulation of translation
D	0030308	biological_process	negative regulation of cell growth
D	0030371	molecular_function	translation repressor activity
D	0043022	molecular_function	ribosome binding
E	0003723	molecular_function	RNA binding
E	0003729	molecular_function	mRNA binding
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0004521	molecular_function	RNA endonuclease activity
E	0005515	molecular_function	protein binding
E	0006276	biological_process	plasmid maintenance
E	0006401	biological_process	RNA catabolic process
E	0008285	biological_process	negative regulation of cell population proliferation
E	0016787	molecular_function	hydrolase activity
E	0017148	biological_process	negative regulation of translation
E	0030308	biological_process	negative regulation of cell growth
E	0030371	molecular_function	translation repressor activity
E	0043022	molecular_function	ribosome binding
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0004521	molecular_function	RNA endonuclease activity
F	0005515	molecular_function	protein binding
F	0006276	biological_process	plasmid maintenance
F	0006401	biological_process	RNA catabolic process
F	0008285	biological_process	negative regulation of cell population proliferation
F	0016787	molecular_function	hydrolase activity
F	0017148	biological_process	negative regulation of translation
F	0030308	biological_process	negative regulation of cell growth
F	0030371	molecular_function	translation repressor activity
F	0043022	molecular_function	ribosome binding
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0004518	molecular_function	nuclease activity
G	0004519	molecular_function	endonuclease activity
G	0004521	molecular_function	RNA endonuclease activity
G	0005515	molecular_function	protein binding
G	0006276	biological_process	plasmid maintenance
G	0006401	biological_process	RNA catabolic process
G	0008285	biological_process	negative regulation of cell population proliferation
G	0016787	molecular_function	hydrolase activity
G	0017148	biological_process	negative regulation of translation
G	0030308	biological_process	negative regulation of cell growth
G	0030371	molecular_function	translation repressor activity
G	0043022	molecular_function	ribosome binding
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0004518	molecular_function	nuclease activity
H	0004519	molecular_function	endonuclease activity
H	0004521	molecular_function	RNA endonuclease activity
H	0005515	molecular_function	protein binding
H	0006276	biological_process	plasmid maintenance
H	0006401	biological_process	RNA catabolic process
H	0008285	biological_process	negative regulation of cell population proliferation
H	0016787	molecular_function	hydrolase activity
H	0017148	biological_process	negative regulation of translation
H	0030308	biological_process	negative regulation of cell growth
H	0030371	molecular_function	translation repressor activity
H	0043022	molecular_function	ribosome binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 201

Chain	Residue
A	PHE5
A	LYS11

site_id	AC2
Number of Residues	2
Details	binding site for residue CL B 201

Chain	Residue
B	PHE5
B	LYS11

site_id	AC3
Number of Residues	1
Details	binding site for residue CL B 202

Chain	Residue
B	ILE43

site_id	AC4
Number of Residues	3
Details	binding site for residue CL C 201

Chain	Residue
C	SER4
C	PHE5
C	LYS11

site_id	AC5
Number of Residues	2
Details	binding site for residue CL D 201

Chain	Residue
D	LYS11
D	PHE5

site_id	AC6
Number of Residues	2
Details	binding site for residue CL D 202

Chain	Residue
D	ASN80
G	TRP72

site_id	AC7
Number of Residues	2
Details	binding site for residue CL E 201

Chain	Residue
E	PHE5
E	LYS11

site_id	AC8
Number of Residues	2
Details	binding site for residue CL F 201

Chain	Residue
F	PHE5
F	LYS11

site_id	AC9
Number of Residues	2
Details	binding site for residue CL G 201

Chain	Residue
G	PHE5
G	LYS11

site_id	AD1
Number of Residues	2
Details	binding site for residue CL H 201

Chain	Residue
H	PHE5
H	LYS11

site_id	AD2
Number of Residues	2
Details	binding site for residue CL H 202

Chain	Residue
H	ILE43
H	HOH353

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"evidences":[{"source":"PubMed","id":"19423702","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	16
Details	Site: {"description":"Interaction with HigA","evidences":[{"source":"PubMed","id":"24257752","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)