5IX1
Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and H3K4me3 peptide
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 501 |
| Chain | Residue |
| A | CYS413 |
| A | CYS416 |
| A | CYS435 |
| A | CYS446 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for residue ANP A 502 |
| Chain | Residue |
| A | MET72 |
| A | MET80 |
| A | SER86 |
| A | LYS88 |
| A | GLY98 |
| A | LEU99 |
| A | TYR100 |
| A | GLY101 |
| A | ASN102 |
| A | GLY103 |
| A | PHE104 |
| A | LYS105 |
| A | THR194 |
| A | LYS358 |
| A | MG503 |
| A | HOH616 |
| A | HOH621 |
| A | GLU35 |
| A | ASN39 |
| A | ASP44 |
| A | VAL45 |
| A | ASP67 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 503 |
| Chain | Residue |
| A | GLU35 |
| A | ASN39 |
| A | ANP502 |
| A | HOH604 |
| A | HOH621 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 501 |
| Chain | Residue |
| B | CYS413 |
| B | CYS416 |
| B | CYS435 |
| B | CYS446 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | binding site for residue ANP B 502 |
| Chain | Residue |
| B | GLU35 |
| B | ASN39 |
| B | ASP44 |
| B | VAL45 |
| B | ASP67 |
| B | MET72 |
| B | MET80 |
| B | SER86 |
| B | LYS88 |
| B | GLY98 |
| B | LEU99 |
| B | TYR100 |
| B | GLY101 |
| B | ASN102 |
| B | GLY103 |
| B | PHE104 |
| B | LYS105 |
| B | THR194 |
| B | LYS358 |
| B | MG503 |
| B | HOH601 |
| B | HOH603 |
| B | HOH608 |
| B | HOH609 |
| B | HOH615 |
| B | HOH616 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 503 |
| Chain | Residue |
| B | ASN39 |
| B | ANP502 |
| B | HOH603 |
| B | HOH609 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoarginine; alternate => ECO:0000305 |
| Chain | Residue | Details |
| P | ARG2 | |
| Q | ARG2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by HASPIN => ECO:0000269|PubMed:15681610 |
| Chain | Residue | Details |
| P | THR3 | |
| Q | THR3 | |
| A | CYS435 | |
| A | CYS446 | |
| B | CYS413 | |
| B | CYS416 | |
| B | CYS435 | |
| B | CYS446 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11747826, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| B | LYS280 | |
| B | LYS293 | |
| A | LYS205 | |
| A | LYS280 | |
| Q | M3L4 | |
| P | M3L4 | |
| A | LYS293 | |
| B | LYS191 | |
| B | LYS205 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| P | GLN5 | |
| Q | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| P | THR6 | |
| Q | THR6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000269|PubMed:15485929 |
| Chain | Residue | Details |
| P | ARG8 | |
| Q | ARG8 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:13678296, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| Q | LYS9 | |
| P | LYS9 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15735677, ECO:0000269|PubMed:15870105 |
| Chain | Residue | Details |
| P | SER10 | |
| Q | SER10 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC and CHEK1 => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| P | THR11 | |
| Q | THR11 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| P | LYS14 | |
| Q | LYS14 |
