5ITQ
Crystal Structure of Human NEIL1, Free Protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003684 | molecular_function | damaged DNA binding |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0006284 | biological_process | base-excision repair |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0019104 | molecular_function | DNA N-glycosylase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Schiff-base intermediate with DNA => ECO:0000305 |
| Chain | Residue | Details |
| A | PRO2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| A | GLU3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor; for beta-elimination activity => ECO:0000305 |
| Chain | Residue | Details |
| A | LYS54 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN176 |
