5ITC

2.2-Angstrom in meso crystal structure of Haloquadratum Walsbyi Bacteriorhodopsin (HwBR) from Styrene Maleic Acid (SMA) Polymer Nanodiscs

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0007602	biological_process	phototransduction
A	0009881	molecular_function	photoreceptor activity
A	0016020	cellular_component	membrane
A	1902600	biological_process	proton transmembrane transport
B	0005216	molecular_function	monoatomic ion channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0007602	biological_process	phototransduction
B	0009881	molecular_function	photoreceptor activity
B	0016020	cellular_component	membrane
B	1902600	biological_process	proton transmembrane transport
C	0005216	molecular_function	monoatomic ion channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0007602	biological_process	phototransduction
C	0009881	molecular_function	photoreceptor activity
C	0016020	cellular_component	membrane
C	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue RET A 301

Chain	Residue
A	TYR91
A	LYS224
A	TRP94
A	THR97
A	THR98
A	SER149
A	THR150
A	TRP190
A	TYR193
A	ASP220

---

site_id	AC2
Number of Residues	8
Details	binding site for residue OLC A 302

Chain	Residue
A	ILE35
A	GLY38
A	LYS47
A	TYR50
A	ILE54
A	ALA58
B	ILE122
B	PHE155

---

site_id	AC3
Number of Residues	7
Details	binding site for residue OLB A 303

Chain	Residue
A	LEU95
A	PRO99
A	LEU103
A	LEU107
A	ALA111
A	OLB305
C	PHE96

---

site_id	AC4
Number of Residues	3
Details	binding site for residue OLC A 304

Chain	Residue
A	THR150
A	MET153
A	TYR158

---

site_id	AC5
Number of Residues	11
Details	binding site for residue OLB A 305

Chain	Residue
A	GLU48
A	LEU55
A	SER63
A	LEU100
A	OLB303
B	GLN113
B	GLY117
B	ALA124
B	PHE125
B	VAL128
B	HOH420

---

site_id	AC6
Number of Residues	5
Details	binding site for residue OLB A 306

Chain	Residue
A	PHE96
B	LEU95
B	PRO99
B	LEU103
B	VAL128

---

site_id	AC7
Number of Residues	5
Details	binding site for residue OLB B 302

Chain	Residue
B	MET153
B	TYR158
B	VAL161
B	ALA162
B	VAL195

---

site_id	AC8
Number of Residues	8
Details	binding site for residue OLB B 303

Chain	Residue
B	ILE35
B	GLY38
B	LEU39
B	LYS47
B	VAL51
B	ILE54
B	ALA61
C	PHE155

---

site_id	AC9
Number of Residues	9
Details	binding site for residue OLB C 302

Chain	Residue
A	GLN113
A	GLY117
A	GLY121
A	VAL128
A	HOH423
C	GLU48
C	LEU55
C	ILE59
C	PHE96

---

site_id	AD1
Number of Residues	15
Details	binding site for residue OLC C 303

Chain	Residue
B	PRO44
B	LYS47
B	GLU48
B	VAL51
B	SER63
B	PHE96
C	ARG114
C	ASP115
C	GLY117
C	ALA118
C	GLY121
C	ALA124
C	PHE125
C	VAL128
C	TYR159

---

site_id	AD2
Number of Residues	10
Details	binding site for residue OLB C 304

Chain	Residue
A	PHE125
A	SER152
A	PHE155
C	MET31
C	ILE35
C	GLY38
C	LEU39
C	LYS47
C	ILE54
C	HOH407

---

site_id	AD3
Number of Residues	20
Details	binding site for Di-peptide RET B 301 and LYS B 224

Chain	Residue
B	SER149
B	THR150
B	TRP190
B	TYR193
B	ASP220
B	LEU221
B	VAL222
B	ALA223
B	VAL225
B	GLY226
B	GLY228
B	HOH409
B	ILE56
B	ALA60
B	ASP93
B	TRP94
B	THR97
B	THR98
B	MET126
B	TRP146

---

site_id	AD4
Number of Residues	19
Details	binding site for Di-peptide RET C 301 and LYS C 224

Chain	Residue
C	ILE56
C	ALA60
C	ASP93
C	TRP94
C	THR97
C	THR98
C	MET126
C	SER149
C	THR150
C	TRP190
C	TYR193
C	ASP220
C	LEU221
C	VAL222
C	ALA223
C	VAL225
C	GLY226
C	GLY228
C	HOH412

---

Functional Information from PROSITE/UniProt

site_id	PS00327
Number of Residues	12
Details	BACTERIAL_OPSIN_RET Bacterial rhodopsins retinal binding site. FMVLDLvAKvGF

Chain	Residue	Details
A	PHE216-PHE227

---

site_id	PS00950
Number of Residues	13
Details	BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYaDWlFTTPLLL

Chain	Residue	Details
A	ARG90-LEU102

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	420
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	GLU16-ALA36
B	TYR91-ALA111
B	ILE116-THR136
B	ALA144-PHE164
B	ILE185-ALA205
B	GLU212-LEU232
C	GLU16-ALA36
C	VAL51-PHE71
C	TYR91-ALA111
C	ILE116-THR136
C	ALA144-PHE164
A	VAL51-PHE71
C	ILE185-ALA205
C	GLU212-LEU232
A	TYR91-ALA111
A	ILE116-THR136
A	ALA144-PHE164
A	ILE185-ALA205
A	GLU212-LEU232
B	GLU16-ALA36
B	VAL51-PHE71

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Primary proton acceptor => ECO:0000250

Chain	Residue	Details
A	ASP93
B	ASP93
C	ASP93

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000250

Chain	Residue	Details
A	GLN7
B	GLN7
C	GLN7

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: N6-(retinylidene)lysine => ECO:0000250

Chain	Residue	Details
A	LYS224
B	LYS224
C	LYS224

---