Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 401 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | CYS290 |
| A | HOH1677 |
| A | HOH2095 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | ALA298 |
| A | GLY299 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue PGE A 403 |
| Chain | Residue |
| A | SER189 |
| A | GLU196 |
| A | TRP197 |
| A | THR198 |
| A | ASP215 |
| A | HOH1067 |
| A | HOH1116 |
| A | ALA187 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 404 |
| Chain | Residue |
| A | THR57 |
| A | ILE58 |
| A | HOH1640 |
| A | HOH2110 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 405 |
| Chain | Residue |
| A | SER233 |
| A | ALA237 |
| A | HOH1791 |
| A | HOH2198 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 406 |
| Chain | Residue |
| A | GLY82 |
| A | SER113 |
| A | SER114 |
| A | SER115 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 A 407 |
| Chain | Residue |
| A | ASP15 |
| A | VAL248 |
| A | PHE280 |
| A | ILE283 |
| A | PHE291 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue 6LZ A 408 |
| Chain | Residue |
| A | TYR79 |
| A | GLY80 |
| A | ASP81 |
| A | SER83 |
| A | PHE116 |
| A | LEU125 |
| A | GLY221 |
| A | THR222 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 409 |
| Chain | Residue |
| A | SER297 |
| A | ALA298 |
| A | GLY301 |
| A | ILE302 |
| A | ASN303 |
| A | HOH867 |
| A | HOH1038 |
| A | HOH1071 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
