5IRP
Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 401 |
| Chain | Residue |
| A | ASN132 |
| A | ARG139 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue UAH A 402 |
| Chain | Residue |
| A | ARG225 |
| A | GLY227 |
| A | ILE228 |
| A | TYR364 |
| A | HOH508 |
| A | HOH518 |
| A | HOH581 |
| B | CO2405 |
| A | LYS39 |
| A | TYR43 |
| A | LEU85 |
| A | ARG139 |
| A | HIS169 |
| A | ASN209 |
| A | THR210 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue TRS A 403 |
| Chain | Residue |
| A | ASP174 |
| A | PRO235 |
| A | TYR364 |
| A | HOH555 |
| A | HOH581 |
| B | TYR272 |
| B | HOH602 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 404 |
| Chain | Residue |
| A | LYS159 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 405 |
| Chain | Residue |
| A | LYS196 |
| A | HOH566 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | GLU329 |
| A | ASN330 |
| A | GLU332 |
| A | HOH672 |
| B | GLU279 |
| B | GLU329 |
| B | ASN330 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 407 |
| Chain | Residue |
| A | ARG372 |
| A | HOH721 |
| B | ARG372 |
| B | HOH550 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 408 |
| Chain | Residue |
| A | GLN107 |
| A | HOH691 |
| A | HOH769 |
| B | GLN335 |
| B | HOH764 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 409 |
| Chain | Residue |
| A | ASN301 |
| A | HOH753 |
| B | ASN301 |
| B | HOH729 |
| B | HOH795 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 410 |
| Chain | Residue |
| A | HOH519 |
| A | HOH526 |
| A | HOH624 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 411 |
| Chain | Residue |
| A | GLN107 |
| A | HOH750 |
| A | HOH760 |
| A | HOH834 |
| B | HOH585 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 412 |
| Chain | Residue |
| A | LEU155 |
| A | LYS156 |
| A | SER158 |
| A | LEU161 |
| A | HOH645 |
| A | HOH755 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 413 |
| Chain | Residue |
| A | HOH528 |
| A | HOH528 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 414 |
| Chain | Residue |
| A | TYR276 |
| A | ILE277 |
| A | GLU282 |
| A | HOH546 |
| A | HOH792 |
| A | HOH811 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 415 |
| Chain | Residue |
| A | HOH515 |
| A | HOH732 |
| A | HOH816 |
| B | HOH754 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 416 |
| Chain | Residue |
| A | TYR272 |
| A | ARG297 |
| A | ARG317 |
| A | HOH576 |
| B | TRS404 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 417 |
| Chain | Residue |
| A | MET1 |
| A | HOH698 |
| A | HOH831 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 418 |
| Chain | Residue |
| A | HOH630 |
| A | HOH713 |
| A | HOH720 |
| site_id | AE1 |
| Number of Residues | 8 |
| Details | binding site for residue CO2 B 401 |
| Chain | Residue |
| A | TYR272 |
| A | THR319 |
| A | MET320 |
| B | LYS39 |
| B | ARG139 |
| B | UAH403 |
| B | HOH606 |
| B | HOH723 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 402 |
| Chain | Residue |
| B | ASN132 |
| B | ARG139 |
| site_id | AE3 |
| Number of Residues | 14 |
| Details | binding site for residue UAH B 403 |
| Chain | Residue |
| B | ASN209 |
| B | THR210 |
| B | ARG225 |
| B | GLY227 |
| B | ILE228 |
| B | TYR364 |
| B | CO2401 |
| B | HOH513 |
| B | HOH525 |
| B | HOH542 |
| B | LYS39 |
| B | TYR43 |
| B | ARG139 |
| B | HIS169 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue TRS B 404 |
| Chain | Residue |
| A | TYR272 |
| A | CL416 |
| A | HOH565 |
| B | ASP174 |
| B | PRO235 |
| B | TYR364 |
| B | HOH596 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue CO2 B 405 |
| Chain | Residue |
| A | LYS39 |
| A | ARG139 |
| A | UAH402 |
| B | TYR272 |
| B | THR319 |
| B | MET320 |
| B | HOH704 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 406 |
| Chain | Residue |
| B | ALA124 |
| B | ARG126 |
| B | PHE160 |
| site_id | AE7 |
| Number of Residues | 1 |
| Details | binding site for residue PEG B 407 |
| Chain | Residue |
| B | LYS196 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 408 |
| Chain | Residue |
| A | GLU279 |
| A | GLU329 |
| B | LYS310 |
| B | LEU327 |
| B | GLU329 |
| B | ASN330 |
| B | HOH661 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 409 |
| Chain | Residue |
| A | HOH799 |
| A | HOH806 |
| B | HOH536 |
| B | HOH623 |
| B | HOH781 |
| B | HOH811 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 410 |
| Chain | Residue |
| A | GLN335 |
| A | HOH777 |
| B | GLN107 |
| B | HOH688 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 411 |
| Chain | Residue |
| A | HOH541 |
| A | HOH623 |
| A | HOH795 |
| B | HOH568 |
| B | HOH645 |
| B | HOH810 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 412 |
| Chain | Residue |
| B | HOH665 |
| B | HOH665 |
| B | HOH815 |
| B | HOH815 |
| B | HOH830 |
| B | HOH830 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue MG B 413 |
| Chain | Residue |
| A | HOH775 |
| B | HOH503 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 414 |
| Chain | Residue |
| A | HOH656 |
| A | HOH826 |
| B | GLN107 |
| B | HOH806 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 415 |
| Chain | Residue |
| B | LEU155 |
| B | LYS156 |
| B | SER158 |
| B | LEU161 |
| B | HOH752 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 416 |
| Chain | Residue |
| B | ALA97 |
| B | ASN100 |
| B | ARG126 |
| B | HOH576 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 417 |
| Chain | Residue |
| B | TYR276 |
| B | GLU282 |
| B | HOH633 |
| B | HOH725 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 418 |
| Chain | Residue |
| B | HOH557 |
| B | HOH586 |
| B | HOH770 |
| B | HOH802 |
| site_id | AG1 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 419 |
| Chain | Residue |
| B | TYR272 |
| B | ARG297 |
| B | ARG317 |
| B | HOH622 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 420 |
| Chain | Residue |
| B | MET1 |
| B | GLU11 |
| B | HOH660 |
| B | HOH828 |
| site_id | AG3 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 421 |
| Chain | Residue |
| B | HOH517 |
| B | HOH535 |
| B | HOH637 |
Functional Information from PROSITE/UniProt
| site_id | PS00395 |
| Number of Residues | 11 |
| Details | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AVvKANGYGHG |
| Chain | Residue | Details |
| A | ALA36-GLY46 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor; specific for D-alanine => ECO:0000255|HAMAP-Rule:MF_01201 |
| Chain | Residue | Details |
| A | LYS39 | |
| B | LYS39 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor; specific for L-alanine => ECO:0000255|HAMAP-Rule:MF_01201 |
| Chain | Residue | Details |
| A | TYR272 | |
| B | TYR272 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01201 |
| Chain | Residue | Details |
| A | ARG139 | |
| A | MET320 | |
| B | ARG139 | |
| B | MET320 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255|HAMAP-Rule:MF_01201 |
| Chain | Residue | Details |
| A | LYS39 | |
| B | LYS39 |
