5IQ4
Crystal structure of RnTmm mutant Y207S soaking
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0034899 | molecular_function | trimethylamine monooxygenase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| B | 0034899 | molecular_function | trimethylamine monooxygenase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | binding site for residue NAP A 501 |
| Chain | Residue |
| A | ASN73 |
| A | SER207 |
| A | SER208 |
| A | ARG229 |
| A | SER230 |
| A | CYS271 |
| A | THR272 |
| A | GLY273 |
| A | ASN291 |
| A | ASP317 |
| A | GLN318 |
| A | PHE165 |
| A | FAD502 |
| A | HOH601 |
| A | HOH617 |
| A | HOH640 |
| A | HOH647 |
| A | HOH677 |
| A | HOH714 |
| A | HOH739 |
| A | HOH790 |
| A | HOH802 |
| A | ASN169 |
| A | HOH857 |
| A | HOH895 |
| A | HOH897 |
| A | HOH913 |
| A | HOH926 |
| A | PRO171 |
| A | TYR173 |
| A | MET203 |
| A | GLY204 |
| A | ALA205 |
| A | SER206 |
| site_id | AC2 |
| Number of Residues | 35 |
| Details | binding site for residue FAD A 502 |
| Chain | Residue |
| A | GLY9 |
| A | GLY11 |
| A | PRO12 |
| A | SER13 |
| A | PHE37 |
| A | GLU38 |
| A | LYS39 |
| A | GLN40 |
| A | GLY45 |
| A | LEU46 |
| A | TRP47 |
| A | HIS63 |
| A | SER65 |
| A | MET66 |
| A | SER72 |
| A | ASN73 |
| A | LEU79 |
| A | PRO125 |
| A | VAL126 |
| A | ALA161 |
| A | SER162 |
| A | GLY163 |
| A | PHE165 |
| A | PHE280 |
| A | GLN318 |
| A | THR321 |
| A | PHE322 |
| A | NAP501 |
| A | HOH634 |
| A | HOH684 |
| A | HOH701 |
| A | HOH778 |
| A | HOH812 |
| A | HOH822 |
| A | HOH923 |
| site_id | AC3 |
| Number of Residues | 30 |
| Details | binding site for residue NAP B 501 |
| Chain | Residue |
| B | ASN73 |
| B | PHE165 |
| B | ASN169 |
| B | PRO171 |
| B | TYR173 |
| B | MET203 |
| B | ALA205 |
| B | SER206 |
| B | SER207 |
| B | SER208 |
| B | ARG229 |
| B | SER230 |
| B | CYS271 |
| B | THR272 |
| B | GLY273 |
| B | ASP317 |
| B | GLN318 |
| B | FAD502 |
| B | HOH651 |
| B | HOH669 |
| B | HOH671 |
| B | HOH748 |
| B | HOH758 |
| B | HOH761 |
| B | HOH767 |
| B | HOH839 |
| B | HOH843 |
| B | HOH850 |
| B | HOH885 |
| B | HOH896 |
| site_id | AC4 |
| Number of Residues | 36 |
| Details | binding site for residue FAD B 502 |
| Chain | Residue |
| B | GLY9 |
| B | GLY11 |
| B | PRO12 |
| B | SER13 |
| B | PHE37 |
| B | GLU38 |
| B | LYS39 |
| B | GLN40 |
| B | GLY45 |
| B | LEU46 |
| B | TRP47 |
| B | HIS63 |
| B | SER65 |
| B | MET66 |
| B | SER72 |
| B | ASN73 |
| B | LEU79 |
| B | PRO125 |
| B | VAL126 |
| B | ALA161 |
| B | SER162 |
| B | GLY163 |
| B | PHE165 |
| B | PHE280 |
| B | GLN318 |
| B | THR321 |
| B | PHE325 |
| B | NAP501 |
| B | HOH614 |
| B | HOH625 |
| B | HOH668 |
| B | HOH721 |
| B | HOH788 |
| B | HOH789 |
| B | HOH849 |
| B | HOH876 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 26 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27997715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GSN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IQ1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IQ4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27997715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IQ1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27997715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IQ1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IQ4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27997715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GSN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IQ4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
