5IOY
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with N-(cyclopentylmethyl)pyrrolidine-1-carboxamide at 1.77A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue 6C5 A 301 |
| Chain | Residue |
| A | PHE110 |
| A | MET142 |
| A | THR149 |
| A | ASN176 |
| A | ASN179 |
| A | TRP207 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 6C5 A 302 |
| Chain | Residue |
| A | PHE184 |
| A | HOH413 |
| A | PHE114 |
| A | TRP138 |
| A | GLU180 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ASP98 |
| A | ARG99 |
| A | HOH410 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue 6C5 A 304 |
| Chain | Residue |
| A | MET102 |
| A | TRP103 |
| A | TYR148 |
| A | VAL152 |
| A | GLU156 |
| A | TYR212 |
| A | HOH406 |
