5IOL

Crystal structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0006166	biological_process	purine ribonucleoside salvage
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0032261	biological_process	purine nucleotide salvage
A	0034214	biological_process	protein hexamerization
A	0042802	molecular_function	identical protein binding
A	0043531	molecular_function	ADP binding
B	0000166	molecular_function	nucleotide binding
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0006166	biological_process	purine ribonucleoside salvage
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009165	biological_process	nucleotide biosynthetic process
B	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0032261	biological_process	purine nucleotide salvage
B	0034214	biological_process	protein hexamerization
B	0042802	molecular_function	identical protein binding
B	0043531	molecular_function	ADP binding
C	0000166	molecular_function	nucleotide binding
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0006166	biological_process	purine ribonucleoside salvage
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009165	biological_process	nucleotide biosynthetic process
C	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0032261	biological_process	purine nucleotide salvage
C	0034214	biological_process	protein hexamerization
C	0042802	molecular_function	identical protein binding
C	0043531	molecular_function	ADP binding
D	0000166	molecular_function	nucleotide binding
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0006166	biological_process	purine ribonucleoside salvage
D	0006183	biological_process	GTP biosynthetic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0009165	biological_process	nucleotide biosynthetic process
D	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0032261	biological_process	purine nucleotide salvage
D	0034214	biological_process	protein hexamerization
D	0042802	molecular_function	identical protein binding
D	0043531	molecular_function	ADP binding
E	0000166	molecular_function	nucleotide binding
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0005524	molecular_function	ATP binding
E	0006166	biological_process	purine ribonucleoside salvage
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009165	biological_process	nucleotide biosynthetic process
E	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
E	0016301	molecular_function	kinase activity
E	0016740	molecular_function	transferase activity
E	0032261	biological_process	purine nucleotide salvage
E	0034214	biological_process	protein hexamerization
E	0042802	molecular_function	identical protein binding
E	0043531	molecular_function	ADP binding
F	0000166	molecular_function	nucleotide binding
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0005524	molecular_function	ATP binding
F	0006166	biological_process	purine ribonucleoside salvage
F	0006183	biological_process	GTP biosynthetic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0009165	biological_process	nucleotide biosynthetic process
F	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
F	0016301	molecular_function	kinase activity
F	0016740	molecular_function	transferase activity
F	0032261	biological_process	purine nucleotide salvage
F	0034214	biological_process	protein hexamerization
F	0042802	molecular_function	identical protein binding
F	0043531	molecular_function	ADP binding
G	0000166	molecular_function	nucleotide binding
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0005524	molecular_function	ATP binding
G	0006166	biological_process	purine ribonucleoside salvage
G	0006183	biological_process	GTP biosynthetic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009165	biological_process	nucleotide biosynthetic process
G	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
G	0016301	molecular_function	kinase activity
G	0016740	molecular_function	transferase activity
G	0032261	biological_process	purine nucleotide salvage
G	0034214	biological_process	protein hexamerization
G	0042802	molecular_function	identical protein binding
G	0043531	molecular_function	ADP binding
H	0000166	molecular_function	nucleotide binding
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0005524	molecular_function	ATP binding
H	0006166	biological_process	purine ribonucleoside salvage
H	0006183	biological_process	GTP biosynthetic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009165	biological_process	nucleotide biosynthetic process
H	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
H	0016301	molecular_function	kinase activity
H	0016740	molecular_function	transferase activity
H	0032261	biological_process	purine nucleotide salvage
H	0034214	biological_process	protein hexamerization
H	0042802	molecular_function	identical protein binding
H	0043531	molecular_function	ADP binding
I	0000166	molecular_function	nucleotide binding
I	0004550	molecular_function	nucleoside diphosphate kinase activity
I	0005524	molecular_function	ATP binding
I	0006166	biological_process	purine ribonucleoside salvage
I	0006183	biological_process	GTP biosynthetic process
I	0006228	biological_process	UTP biosynthetic process
I	0006241	biological_process	CTP biosynthetic process
I	0009165	biological_process	nucleotide biosynthetic process
I	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
I	0016301	molecular_function	kinase activity
I	0016740	molecular_function	transferase activity
I	0032261	biological_process	purine nucleotide salvage
I	0034214	biological_process	protein hexamerization
I	0042802	molecular_function	identical protein binding
I	0043531	molecular_function	ADP binding
J	0000166	molecular_function	nucleotide binding
J	0004550	molecular_function	nucleoside diphosphate kinase activity
J	0005524	molecular_function	ATP binding
J	0006166	biological_process	purine ribonucleoside salvage
J	0006183	biological_process	GTP biosynthetic process
J	0006228	biological_process	UTP biosynthetic process
J	0006241	biological_process	CTP biosynthetic process
J	0009165	biological_process	nucleotide biosynthetic process
J	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
J	0016301	molecular_function	kinase activity
J	0016740	molecular_function	transferase activity
J	0032261	biological_process	purine nucleotide salvage
J	0034214	biological_process	protein hexamerization
J	0042802	molecular_function	identical protein binding
J	0043531	molecular_function	ADP binding
K	0000166	molecular_function	nucleotide binding
K	0004550	molecular_function	nucleoside diphosphate kinase activity
K	0005524	molecular_function	ATP binding
K	0006166	biological_process	purine ribonucleoside salvage
K	0006183	biological_process	GTP biosynthetic process
K	0006228	biological_process	UTP biosynthetic process
K	0006241	biological_process	CTP biosynthetic process
K	0009165	biological_process	nucleotide biosynthetic process
K	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
K	0016301	molecular_function	kinase activity
K	0016740	molecular_function	transferase activity
K	0032261	biological_process	purine nucleotide salvage
K	0034214	biological_process	protein hexamerization
K	0042802	molecular_function	identical protein binding
K	0043531	molecular_function	ADP binding
L	0000166	molecular_function	nucleotide binding
L	0004550	molecular_function	nucleoside diphosphate kinase activity
L	0005524	molecular_function	ATP binding
L	0006166	biological_process	purine ribonucleoside salvage
L	0006183	biological_process	GTP biosynthetic process
L	0006228	biological_process	UTP biosynthetic process
L	0006241	biological_process	CTP biosynthetic process
L	0009165	biological_process	nucleotide biosynthetic process
L	0009202	biological_process	deoxyribonucleoside triphosphate biosynthetic process
L	0016301	molecular_function	kinase activity
L	0016740	molecular_function	transferase activity
L	0032261	biological_process	purine nucleotide salvage
L	0034214	biological_process	protein hexamerization
L	0042802	molecular_function	identical protein binding
L	0043531	molecular_function	ADP binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1572
Details	Domain: {"description":"NDPK-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00706","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00706","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00706","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31103556","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KK8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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